{"id":"W1976686551","doi":"10.1038/ncomms3546","title":"Structure of GrlR–GrlA complex that prevents GrlA activation of virulence genes","year":2013,"lang":"en","type":"article","venue":"Nature Communications","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":false,"ca_institutions":"Trinity Western University; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; State Key Laboratory of Bioreactor Engineering; Biomedical Research Council; Israel Science Foundation; National University of Singapore","keywords":"Virulence; Pathogenicity island; Operon; Gene; Biology; Locus (genetics); Enteropathogenic Escherichia coli; Genetics; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003016479,0.0004000926,0.000471986,0.0003109868,0.0004866843,0.0006641048,0.001350242,0.0007207271,0.00438383],"category_scores_gemma":[0.0005754201,0.0004110732,0.0003906105,0.0001617186,0.000530961,0.0003299787,0.0002820236,0.001614824,0.001101447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001355625,"about_ca_system_score_gemma":0.0006758122,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002042084,"about_ca_topic_score_gemma":0.00139779,"domain_scores_codex":[0.9997301,0.00004804045,0.00002597729,0.00006503133,0.00006051553,0.00007033469],"domain_scores_gemma":[0.9995348,0.00008744759,0.00007429653,0.00007916613,0.0000569143,0.0001672843],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008465227,0.0002118485,0.0001770406,0.00005760432,0.0000344925,0.0001584945,0.00002595326,0.0007839885,0.9950914,0.0009920814,0.0005509329,0.001069509],"study_design_scores_gemma":[0.0001824936,0.0002536657,0.0009864991,0.000009622203,0.00001949201,0.0002076942,0.00001897761,0.00330036,0.9910265,0.0001536531,0.003818406,0.00002267922],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874359,0.0009591832,0.00601333,0.0007981904,0.000348051,0.00007845287,0.0008556125,0.0003760029,0.003135199],"genre_scores_gemma":[0.9906204,0.0001738964,0.004007662,0.0003076037,0.00003637052,0.00003620317,0.00167675,0.00006699599,0.003074112],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00438383,"threshold_uncertainty_score":0.01466537,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03418832377378561,"score_gpt":0.3373425245708497,"score_spread":0.3031542007970641,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}