{"id":"W1976686551","doi":"10.1038/ncomms3546","title":"Structure of GrlR–GrlA complex that prevents GrlA activation of virulence genes","year":2013,"lang":"en","type":"article","venue":"Nature Communications","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":false,"ca_institutions":"Trinity Western University; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; State Key Laboratory of Bioreactor Engineering; Biomedical Research Council; Israel Science Foundation; National University of Singapore","keywords":"Virulence; Pathogenicity island; Operon; Gene; Biology; Locus (genetics); Enteropathogenic Escherichia coli; Genetics; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007301816,0.0001017616,0.0001417492,0.00004432897,0.0001085858,0.000008751334,0.0008901551,0.0002059338,0.0000314563],"category_scores_gemma":[0.0002184765,0.00009053489,0.00005983613,0.0001610574,0.000246848,0.00001094533,0.0006239053,0.0002807751,0.00000135962],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000115825,"about_ca_system_score_gemma":0.00005495233,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007213721,"about_ca_topic_score_gemma":0.0001277959,"domain_scores_codex":[0.9992288,0.0001442462,0.000176051,0.0001446572,0.0001805706,0.0001256237],"domain_scores_gemma":[0.9981319,0.00007152805,0.0001694987,0.001228038,0.0003644896,0.00003455912],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000008867804,0.00008324963,0.01079969,0.00002985311,0.00007155124,1.367943e-8,0.00005557572,0.00001245986,0.9849386,0.0004731462,0.002168888,0.001358158],"study_design_scores_gemma":[0.0002819436,0.0001074515,0.1857241,0.0000404717,0.00001832871,0.0000012883,0.0001753901,0.0002506281,0.7952201,0.0004686109,0.01756647,0.0001452809],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931865,0.004461722,0.0001306431,0.0007539722,0.00003138968,0.00039251,0.0000685955,0.000008125015,0.0009665692],"genre_scores_gemma":[0.9898853,0.001930085,0.007694509,0.00009345276,0.00002476105,0.000033562,0.0002167841,0.00001112942,0.0001104428],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1897185,"threshold_uncertainty_score":0.3691906,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03418832377378561,"score_gpt":0.3373425245708497,"score_spread":0.3031542007970641,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}