{"id":"W1976694579","doi":"10.1021/ed100171g","title":"Rapid and Convenient Synthesis of the 1,4-Dihydropyridine Privileged Structure","year":2010,"lang":"en","type":"article","venue":"Journal of Chemical Education","topic":"Multicomponent Synthesis of Heterocycles","field":"Chemistry","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Dihydropyridine; Microscale chemistry; Chemistry; Combinatorial chemistry; Nuclear magnetic resonance spectroscopy; Nanotechnology; Biochemical engineering; Organic chemistry; Computational chemistry; Calcium; Materials science; Mathematics; Mathematics education; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001285484,0.0003182307,0.0002431413,0.0001942572,0.0002026389,0.0002022227,0.0003197954,0.0002320244,0.003499334],"category_scores_gemma":[0.000111261,0.000164674,0.0001623051,0.0001518629,0.0001698162,0.0003103595,0.0003507262,0.0004876451,0.001305908],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001841203,"about_ca_system_score_gemma":0.000395219,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002618353,"about_ca_topic_score_gemma":0.000689579,"domain_scores_codex":[0.9999127,0.000008987909,0.000005107869,0.00002526384,0.00002172987,0.0000262177],"domain_scores_gemma":[0.9999549,0.000006553908,0.000008287871,0.000009539282,0.000006597002,0.0000140734],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007224447,0.00008528755,0.00009548099,0.0002317361,0.000009053751,0.0003433079,0.00008953577,0.0009007186,0.9628634,0.004421174,0.000587247,0.03030076],"study_design_scores_gemma":[0.00004691303,0.002008048,0.001032983,0.0000221862,0.00001816058,0.0009703854,0.00003447866,0.001628639,0.9576103,0.001167022,0.0354248,0.00003604529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7754424,0.009746751,0.1525081,0.0005093151,0.0003735504,0.0008270059,0.001717559,0.0009936036,0.05788182],"genre_scores_gemma":[0.9338009,0.003973268,0.05118895,0.0001401322,0.00004586172,0.0001770569,0.0004421333,0.00006919288,0.01016251],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003499334,"threshold_uncertainty_score":0.01170641,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006034687946853164,"score_gpt":0.2321327542522641,"score_spread":0.2260980663054109,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}