{"id":"W1976720506","doi":"10.1016/s0306-4522(02)00278-6","title":"Chronic estrogen deficiency leads to molecular aberrations related to neurodegenerative changes in follitropin receptor knockout female mice","year":2002,"lang":"en","type":"article","venue":"Neuroscience","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Clinical Research Institute; McGill University","funders":"","keywords":"Endocrinology; Internal medicine; Choline acetyltransferase; Knockout mouse; Biology; Neurite; Estrogen receptor; Estrogen receptor beta; Estrogen; Central nervous system; Hippocampus; Hippocampal formation; Receptor; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002309802,0.001021015,0.0006167987,0.002442343,0.0005759315,0.0006103366,0.0006192561,0.001035538,0.005582196],"category_scores_gemma":[0.0002858674,0.0007219094,0.0005609842,0.0006197944,0.0008319225,0.0005711224,0.0004927628,0.00138772,0.001156994],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004485287,"about_ca_system_score_gemma":0.0003313629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00138223,"about_ca_topic_score_gemma":0.002145696,"domain_scores_codex":[0.9996152,0.0000322654,0.00005781781,0.0001250859,0.00008175303,0.00008789074],"domain_scores_gemma":[0.9990835,0.0001125042,0.0004346857,0.00007074744,0.00005407319,0.0002444818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005735483,0.00006626605,0.0004198565,0.00002944728,0.00001749265,0.0005551429,0.00004217404,0.00003291143,0.9972154,0.0001680489,0.00006327512,0.0008164311],"study_design_scores_gemma":[0.0001503344,0.0004313729,0.0201852,0.00003003233,0.0001395523,0.003877975,0.000228464,0.0005775656,0.9710749,0.0003191209,0.002955964,0.00002943682],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917324,0.001260746,0.002447552,0.0003310301,0.00007687193,0.0000273603,0.002578873,0.0002260971,0.001319166],"genre_scores_gemma":[0.9726586,0.001968245,0.003038639,0.0002025619,0.00005485692,0.0001235745,0.002006128,0.0003413036,0.0196061],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005582196,"threshold_uncertainty_score":0.01867425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01215579797196356,"score_gpt":0.2549206008535362,"score_spread":0.2427648028815726,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}