{"id":"W1976729863","doi":"10.1165/ajrcmb.23.3.4057","title":"Endothelin-1 Changes Polymorphonuclear Leukocytes' Deformability and CD11b Expression and Promotes Their Retention in the Lung","year":2000,"lang":"en","type":"article","venue":"American Journal of Respiratory Cell and Molecular Biology","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"","keywords":"Sodium nitroprusside; Nitric oxide; In vivo; Chemistry; Endothelin 1; In vitro; Granulocyte; Molecular biology; Internal medicine; Endocrinology; Andrology; Immunology; Biology; Biochemistry; Medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001697901,0.0002088972,0.0002746073,0.0001989343,0.0001636447,0.0003132856,0.000158051,0.000370215,0.001404393],"category_scores_gemma":[0.0001955324,0.0001610948,0.0001785396,0.0001238059,0.000174859,0.0003689261,0.0001723959,0.0005514835,0.0002144205],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001820232,"about_ca_system_score_gemma":0.00009233049,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003528605,"about_ca_topic_score_gemma":0.0005191435,"domain_scores_codex":[0.9998068,0.00005574492,0.00001475801,0.00003416805,0.00004145421,0.00004700918],"domain_scores_gemma":[0.9998759,0.00001987793,0.00004433698,0.000009765333,0.00001181978,0.00003829442],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003194702,0.0000389866,0.001042661,0.00003273022,0.000005626588,0.0001069562,0.00001911473,0.00001555558,0.9964641,0.00003259165,0.00002886375,0.001893427],"study_design_scores_gemma":[0.00007647837,0.001566104,0.207187,0.00002957724,0.00006483031,0.001768607,0.000248985,0.001529773,0.7847224,0.0001578509,0.00263293,0.00001543292],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945898,0.00384355,0.000822714,0.00008128976,0.00002136921,0.000009822988,0.00005414296,0.00001317223,0.0005640882],"genre_scores_gemma":[0.9960541,0.001599946,0.0007089179,0.00005368615,0.00002113422,0.00001695889,0.00008290528,0.000004550863,0.001457725],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001404393,"threshold_uncertainty_score":0.004698217,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008352093717210815,"score_gpt":0.2463975489698126,"score_spread":0.2380454552526018,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}