{"id":"W1976735289","doi":"10.1021/bc100178z","title":"Facile Synthesis of Advanced Photodynamic Molecular Beacon Architectures","year":2010,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"Photodynamic Therapy Research Studies","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Photodynamic therapy; Molecular beacon; Combinatorial chemistry; Nanotechnology; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001471552,0.0002348818,0.000431855,0.00005434838,0.00005110394,0.00000876448,0.0002227641,0.0001529363,0.0004602138],"category_scores_gemma":[0.0004866202,0.0002014904,0.0001856969,0.0001406563,0.000400982,0.00001831484,0.00009385755,0.0004551472,0.00001134573],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004054668,"about_ca_system_score_gemma":0.0001169135,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002862466,"about_ca_topic_score_gemma":0.000005713917,"domain_scores_codex":[0.9986503,0.00001519108,0.0002814463,0.0003606473,0.0003291205,0.0003633609],"domain_scores_gemma":[0.9988802,0.0001157112,0.0001080427,0.0005977203,0.0001169439,0.0001813936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002731944,0.0001094785,0.0001936263,0.000439245,0.0001448744,0.0000427922,0.0000601787,0.000006169502,0.992398,0.000008120937,0.00004073575,0.00628361],"study_design_scores_gemma":[0.0007518533,0.00005574295,0.001520165,0.0001015944,0.00004562405,0.00005717102,0.00008242986,0.00007397477,0.9959252,0.0001275531,0.001080999,0.0001776514],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904588,0.0002840619,0.000008421363,0.0002508849,0.00004976126,0.0003943906,0.0001191223,0.00008083499,0.008353705],"genre_scores_gemma":[0.9983333,0.00006886999,0.0006157233,0.00006534199,0.00004911564,0.0001286435,0.00002700838,0.00003531458,0.0006766256],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007874539,"threshold_uncertainty_score":0.8216541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005188354008062273,"score_gpt":0.2640416651929515,"score_spread":0.2588533111848892,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}