{"id":"W1976753737","doi":"10.1139/v09-036","title":"Chiral α-substituted allylboronates in a one-pot three-component asymmetric allylic alkylation/carbonyl allylation reaction sequence — Applications to the syntheses of (+)-(3 <i>R</i> ,5 <i>R</i> )-3-hydroxy-5-decanolide and (–)-massoialactone","year":2009,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthetic Organic Chemistry Methods","field":"Chemistry","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Allylic rearrangement; Reagent; Aldehyde; Regioselectivity; Enantioselective synthesis; Tsuji–Trost reaction; Alkylation; Phosphoramidite; Organic chemistry; Catalysis; Selectivity; Lewis acids and bases; Medicinal chemistry; Combinatorial chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002154277,0.0007034038,0.0003688881,0.0002097579,0.0001318374,0.0002896669,0.0003330456,0.0003221609,0.0008265774],"category_scores_gemma":[0.0001138976,0.0001976698,0.0002036098,0.0002392462,0.0002533032,0.0002928771,0.000378685,0.0006092893,0.0007788812],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003037833,"about_ca_system_score_gemma":0.0004744955,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005082488,"about_ca_topic_score_gemma":0.001304727,"domain_scores_codex":[0.9998876,0.00001441637,0.00001261477,0.00002328947,0.00002856176,0.00003347485],"domain_scores_gemma":[0.9999353,0.000005569461,0.00002148549,0.000008355323,0.00000934515,0.00002001312],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008219735,0.00003674782,0.00007066715,0.00007500402,0.000007928605,0.00007452872,0.00003151275,0.0001649929,0.9949202,0.0002244235,0.00002827372,0.004283519],"study_design_scores_gemma":[0.00002364179,0.0002406229,0.0002681255,0.000004864158,0.00001331926,0.0001347438,0.00001066112,0.0004268926,0.9968073,0.00003319734,0.002028544,0.000008123208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9491876,0.001697734,0.0393338,0.0001347203,0.00009563237,0.0004603032,0.0003542114,0.0005457682,0.008190197],"genre_scores_gemma":[0.9750234,0.0009712941,0.01962218,0.00004665559,0.00001276172,0.0001123993,0.0002239945,0.00004477873,0.003942637],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008265774,"threshold_uncertainty_score":0.002765119,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02909122289069449,"score_gpt":0.2568447393455763,"score_spread":0.2277535164548818,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}