{"id":"W1976757622","doi":"10.1038/nsb832","title":"The structural basis for specificity in human ABO(H) blood group biosynthesis","year":2002,"lang":"en","type":"article","venue":"Nature Structural Biology","topic":"Blood groups and transfusion","field":"Medicine","cited_by":246,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; Institute for Biological Sciences; University of Ottawa","funders":"","keywords":"Glycosyltransferase; Galactosyltransferase; ABO blood group system; Biosynthesis; Enzyme; Transferase; Acceptor; Residue (chemistry); Chemistry; Biochemistry; Antigen; Stereochemistry; Amino acid; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001756598,0.0002591481,0.0002297922,0.0001130085,0.0002991973,0.0004458967,0.0002822234,0.0004773877,0.001731249],"category_scores_gemma":[0.0003067834,0.0001751074,0.0002016165,0.00009832023,0.0003214525,0.0002575662,0.0002574778,0.0006564648,0.0007236307],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002497544,"about_ca_system_score_gemma":0.0003003322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004417464,"about_ca_topic_score_gemma":0.0004028067,"domain_scores_codex":[0.9999075,0.00002110759,0.000006201295,0.00002056389,0.00001638828,0.00002830046],"domain_scores_gemma":[0.9998608,0.00003783096,0.00002345182,0.00002132044,0.00001884581,0.00003779627],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005602987,0.00007049929,0.002077766,0.00007910588,0.000019154,0.000895488,0.0001278946,0.001702871,0.96392,0.0182451,0.0009233346,0.01137859],"study_design_scores_gemma":[0.00007861634,0.0005214926,0.006758679,0.00002230562,0.00003947547,0.002601874,0.000154081,0.008127391,0.9508316,0.01057345,0.0202521,0.00003891538],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9780335,0.001189174,0.01092134,0.0007308248,0.0001307211,0.00002656957,0.0001545178,0.000166012,0.008647274],"genre_scores_gemma":[0.9966075,0.0002363479,0.001827034,0.0001545253,0.00002042287,0.000004861782,0.0001062333,0.0000136864,0.001029299],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001731249,"threshold_uncertainty_score":0.005791605,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01197391227129495,"score_gpt":0.2750451766708226,"score_spread":0.2630712643995277,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}