{"id":"W1976807738","doi":"10.1523/jneurosci.2404-07.2007","title":"The Inhibition Site on Myelin-Associated Glycoprotein Is within Ig-Domain 5 and Is Distinct from the Sialic Acid Binding Site","year":2007,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's Health Research Institute","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health","keywords":"Chinese hamster ovary cell; Myelin-associated glycoprotein; Sialic acid; Neurite; Glycoprotein; Ganglioside; Binding site; SIGLEC; Molecular biology; Chemistry; Glycan; Biology; Biochemistry; Myelin; Receptor; In vitro; Central nervous system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001265764,0.0001270933,0.0001033499,0.00002899217,0.0004375979,0.0001368534,0.0002691725,0.00006917442,0.000003009473],"category_scores_gemma":[0.00106247,0.00007581244,0.00008724783,0.0001980343,0.000258227,0.00001233202,0.0001002764,0.0002293434,0.000004095262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002604018,"about_ca_system_score_gemma":0.000069754,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001114147,"about_ca_topic_score_gemma":0.00002263582,"domain_scores_codex":[0.998648,0.0001247816,0.0003362329,0.0002440419,0.0004191913,0.0002277584],"domain_scores_gemma":[0.998992,0.0001163696,0.0004470526,0.0002356269,0.00009197932,0.0001169597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001670102,0.00003264715,0.004798286,0.000001208395,0.00000531297,0.00003694865,0.0002740409,0.000008390065,0.9934434,0.000005570036,0.000883633,0.0003436035],"study_design_scores_gemma":[0.000584882,0.0005287598,0.04185542,0.00007785591,0.00002193818,0.00005316203,0.0000992593,0.00009072842,0.9529511,0.0002762249,0.003326194,0.0001344901],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973379,0.0003025279,0.0005137903,0.001235305,0.0003882824,0.0001037416,0.00008753534,0.000004442331,0.00002649456],"genre_scores_gemma":[0.9965372,0.00004893967,0.00008160757,0.003004568,0.0002502458,0.000001216574,0.000004743435,0.00001173811,0.00005971992],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04049227,"threshold_uncertainty_score":0.3365694,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0149752689805238,"score_gpt":0.256409483142247,"score_spread":0.2414342141617232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}