{"id":"W1976840413","doi":"10.1038/ncb1334","title":"Disruption of GW bodies impairs mammalian RNA interference","year":2005,"lang":"en","type":"article","venue":"Nature Cell Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":492,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Argonaute; Gene silencing; RasiRNA; Small interfering RNA; Cell biology; P-bodies; Trans-acting siRNA; RNA; Biology; RNA-induced silencing complex; RNA interference; RNA silencing; Cytoplasm; RNA-induced transcriptional silencing; Stress granule; Messenger RNA; Genetics; Gene; Translation (biology)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002925952,0.0008125668,0.0004176451,0.0006310696,0.0002965036,0.0007090211,0.0005993047,0.0009716965,0.003301588],"category_scores_gemma":[0.0003288657,0.0004478449,0.0005157726,0.000311093,0.0009779428,0.0004795883,0.0007384222,0.001274857,0.001517481],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005062078,"about_ca_system_score_gemma":0.0003490543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007836068,"about_ca_topic_score_gemma":0.001071211,"domain_scores_codex":[0.9995992,0.00005998815,0.00007175097,0.00008673443,0.00009791475,0.00008449396],"domain_scores_gemma":[0.9992861,0.0001609415,0.000230004,0.0001289796,0.00002496712,0.0001689815],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001193399,0.00002671707,0.0001141585,0.00001582026,0.00001078299,0.000106027,0.00001593616,0.0001140001,0.9981849,0.0005129759,0.00007246569,0.0007068712],"study_design_scores_gemma":[0.00001560936,0.00006034359,0.001837402,0.000005042422,0.0000187981,0.0002855233,0.00003171976,0.001133486,0.994767,0.0002158783,0.00162186,0.000007287895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9845825,0.0006317917,0.009526537,0.0003673958,0.0001183066,0.00003399028,0.0009023045,0.0008108061,0.00302631],"genre_scores_gemma":[0.9921964,0.0002595243,0.002465891,0.00009162603,0.0000107898,0.0000231386,0.000575406,0.0002507657,0.004126356],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003301588,"threshold_uncertainty_score":0.01104492,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007359665508317252,"score_gpt":0.2844706555057985,"score_spread":0.2771109899974812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}