{"id":"W1976840413","doi":"10.1038/ncb1334","title":"Disruption of GW bodies impairs mammalian RNA interference","year":2005,"lang":"en","type":"article","venue":"Nature Cell Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":492,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Argonaute; Gene silencing; RasiRNA; Small interfering RNA; Cell biology; P-bodies; Trans-acting siRNA; RNA; Biology; RNA-induced silencing complex; RNA interference; RNA silencing; Cytoplasm; RNA-induced transcriptional silencing; Stress granule; Messenger RNA; Genetics; Gene; Translation (biology)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000141464,0.0001094602,0.0001311241,0.00005260329,0.00003576704,0.000005869698,0.0002135846,0.0004194301,0.00004928684],"category_scores_gemma":[0.00006050246,0.00008738018,0.00007538684,0.00004317274,0.000115289,0.000002922721,0.0001083644,0.0002629159,0.00001644469],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001373942,"about_ca_system_score_gemma":0.00003748708,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001842373,"about_ca_topic_score_gemma":0.00009986658,"domain_scores_codex":[0.9992297,0.00006124598,0.0001555519,0.0002470751,0.00005221513,0.0002542024],"domain_scores_gemma":[0.9995468,0.00001412337,0.00006545774,0.0002296,0.00007986007,0.00006420862],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001007231,0.00003318573,0.004148053,0.00001667351,0.00001353092,8.466677e-7,0.00002342967,0.00000734507,0.9836944,0.0001340968,0.001237122,0.01059056],"study_design_scores_gemma":[0.0003196154,0.0004764867,0.002409072,0.000007535776,0.000005178915,0.00000445059,0.0000497716,0.0000724314,0.9648433,0.00006064744,0.0316372,0.0001142891],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917106,0.00299648,0.0003226115,0.000316945,0.000112208,0.00008612157,0.00001958133,0.000007829256,0.004427592],"genre_scores_gemma":[0.9963776,0.0003953593,0.0005677172,0.0001925281,0.0002443496,0.000006020362,0.0001137964,0.00000878705,0.002093883],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03040008,"threshold_uncertainty_score":0.356326,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007359665508317252,"score_gpt":0.2844706555057985,"score_spread":0.2771109899974812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}