{"id":"W1976936829","doi":"10.1016/j.yrtph.2013.07.007","title":"Genotoxicity of pyrroloquinoline quinone (PQQ) disodium salt (BioPQQ™)","year":2013,"lang":"en","type":"article","venue":"Regulatory Toxicology and Pharmacology","topic":"Microbial metabolism and enzyme function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"Intertek (Canada)","funders":"","keywords":"Pyrroloquinoline quinone; Genotoxicity; In vivo; Micronucleus test; Ames test; In vitro; Chemistry; Molecular biology; Chinese hamster; Micronucleus; Biochemistry; Biology; Toxicity; Genetics; Enzyme; Cofactor; Salmonella","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002194314,0.00021671,0.0003434242,0.00008958928,0.0001061869,0.00000500252,0.0001718638,0.0004512918,0.001054758],"category_scores_gemma":[0.00002487321,0.0002081405,0.00008437358,0.00009118569,0.0004873868,0.00001158868,0.000168466,0.0001643193,0.00003930369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001066822,"about_ca_system_score_gemma":0.00006793127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002954278,"about_ca_topic_score_gemma":0.00001850799,"domain_scores_codex":[0.9985669,0.0002084352,0.0003568892,0.0004216362,0.00006804239,0.0003780922],"domain_scores_gemma":[0.999303,0.0000273807,0.0001679042,0.0002428162,0.0001077664,0.0001511721],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002249756,0.0001579484,0.001598443,0.00005127161,0.0001045191,0.000001735718,0.00003544007,0.00003163851,0.9658307,0.000276798,0.03004785,0.001638705],"study_design_scores_gemma":[0.001303212,0.0005585125,0.03610095,0.000003559122,0.00007939243,0.0000542527,0.00001742306,0.00005596779,0.9078361,0.0001794317,0.05359538,0.0002157943],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950552,0.002455186,0.0002629553,0.0004792847,0.001044239,0.000400697,0.00003963081,0.0000229458,0.0002398335],"genre_scores_gemma":[0.9958522,0.0005744446,0.0002429029,0.001810452,0.0006135418,0.00006495038,0.00006019412,0.00002273653,0.0007586197],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05799455,"threshold_uncertainty_score":0.9998584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007553124135738317,"score_gpt":0.2359108099855627,"score_spread":0.2283576858498244,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}