{"id":"W1976936829","doi":"10.1016/j.yrtph.2013.07.007","title":"Genotoxicity of pyrroloquinoline quinone (PQQ) disodium salt (BioPQQ™)","year":2013,"lang":"en","type":"article","venue":"Regulatory Toxicology and Pharmacology","topic":"Microbial metabolism and enzyme function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"Intertek (Canada)","funders":"","keywords":"Pyrroloquinoline quinone; Genotoxicity; In vivo; Micronucleus test; Ames test; In vitro; Chemistry; Molecular biology; Chinese hamster; Micronucleus; Biochemistry; Biology; Toxicity; Genetics; Enzyme; Cofactor; Salmonella","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001821688,0.0004394873,0.0002829074,0.000243212,0.0001815623,0.0001375777,0.0002120772,0.0004574977,0.002703855],"category_scores_gemma":[0.0001900136,0.0001619351,0.0002870921,0.0002016265,0.0002422079,0.0001661422,0.0001516861,0.0002638871,0.0003105104],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00023927,"about_ca_system_score_gemma":0.0002761516,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002178686,"about_ca_topic_score_gemma":0.00191765,"domain_scores_codex":[0.9998465,0.00005183623,0.0000185697,0.00002572776,0.0000270985,0.00003035041],"domain_scores_gemma":[0.9998426,0.00002979033,0.00003369746,0.00002070129,0.0000391771,0.00003391294],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002288507,0.00009456657,0.001575146,0.0001072286,0.00002154547,0.0001911181,0.00005623333,0.0001304006,0.991557,0.0001464312,0.000159379,0.003672473],"study_design_scores_gemma":[0.00006515058,0.004187905,0.006614983,0.0000122009,0.00004402771,0.0003340021,0.00006726704,0.0003902879,0.9868238,0.00008187869,0.001368959,0.0000096269],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959889,0.001454636,0.00112395,0.0001038317,0.00006188565,0.00003437518,0.0003279435,0.00005595916,0.000848574],"genre_scores_gemma":[0.9968527,0.0006444735,0.0004987337,0.00003931422,0.000009278585,0.00001611696,0.0002864641,0.000004830309,0.001648164],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002703855,"threshold_uncertainty_score":0.009045243,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007553124135738317,"score_gpt":0.2359108099855627,"score_spread":0.2283576858498244,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}