{"id":"W1976943786","doi":"10.1007/s00412-011-0332-y","title":"Point mutations in a Drosophila P element abolish both P element-dependent silencing (PDS) of a transgene and repressor functions","year":2011,"lang":"en","type":"article","venue":"Chromosoma","topic":"Chromosomal and Genetic Variations","field":"Agricultural and Biological Sciences","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"P element; Repressor; Biology; Variegation (histology); Gene silencing; Transposable element; Genetics; Drosophila melanogaster; Gene; Heterochromatin; Point mutation; Transgene; Phenotype; Mutation; Mutant; Gene expression; Chromatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001967028,0.001108069,0.0003180299,0.0007380244,0.0003043834,0.0003079808,0.0007619238,0.0007602489,0.003924792],"category_scores_gemma":[0.0003489078,0.0004718425,0.00058814,0.0003711469,0.0008126241,0.0003918535,0.0008282015,0.001533882,0.001329516],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005198442,"about_ca_system_score_gemma":0.0003645531,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001114077,"about_ca_topic_score_gemma":0.001891719,"domain_scores_codex":[0.999665,0.00004745295,0.00005396327,0.0001004769,0.00009274398,0.00004032295],"domain_scores_gemma":[0.9993876,0.0002088504,0.0001334242,0.00009123509,0.00003442016,0.0001443964],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006126501,0.00002066319,0.0001024865,0.00001527146,0.000006417601,0.0001072628,0.0000100877,0.00003496526,0.9988263,0.0002354264,0.0000204508,0.0005593393],"study_design_scores_gemma":[0.00004666527,0.0001499273,0.003652833,0.000006382831,0.00002825214,0.0008228799,0.00002395223,0.001200926,0.9921943,0.0001185787,0.001742103,0.00001311363],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9797917,0.0004019414,0.01512302,0.0001300489,0.00006798542,0.00007272552,0.0007415258,0.0005261943,0.003144965],"genre_scores_gemma":[0.9886807,0.0002187058,0.004913651,0.00005774638,0.00001555371,0.00005349149,0.0007499736,0.0002395051,0.005070572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003924792,"threshold_uncertainty_score":0.01312971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02564995871131857,"score_gpt":0.2166192776965109,"score_spread":0.1909693189851923,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}