{"id":"W1976965279","doi":"10.1016/s1097-2765(00)00139-8","title":"Direct Binding of the Na–H Exchanger NHE1 to ERM Proteins Regulates the Cortical Cytoskeleton and Cell Shape Independently of H+ Translocation","year":2000,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":409,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"National Institute of Dental and Craniofacial Research; National Institute of General Medical Sciences; National Institutes of Health","keywords":"Moesin; Ezrin; Cell biology; Cytoskeleton; Biology; Radixin; Colocalization; Actin cytoskeleton; Actin; Actin-binding protein; Actin remodeling; Lamellipodium; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001104407,0.0001881903,0.0002324059,0.0001374077,0.000438421,0.0005506691,0.0002895446,0.0003514039,0.002410825],"category_scores_gemma":[0.0002279389,0.0002856631,0.0001897581,0.00009308795,0.0003171627,0.0003230969,0.0004165028,0.0006347997,0.0007748363],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000630099,"about_ca_system_score_gemma":0.000183418,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001039515,"about_ca_topic_score_gemma":0.003808056,"domain_scores_codex":[0.9998549,0.00001463319,0.000004551539,0.00002695917,0.00003570693,0.00006322124],"domain_scores_gemma":[0.9998449,0.00003746848,0.00003313551,0.00002178897,0.00001953793,0.0000431014],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001170021,0.0000194676,0.0001343937,0.00001960031,0.000002954132,0.00003098416,0.00001418666,0.00004764941,0.9981334,0.0003324342,0.0001015978,0.001046367],"study_design_scores_gemma":[0.00004783076,0.00006411723,0.01806679,0.000006284713,0.000009729203,0.0001444564,0.00008100796,0.001817759,0.9761255,0.0002286182,0.003400144,0.000007718618],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919404,0.001422103,0.002370868,0.000337914,0.00006017879,0.00000886315,0.0001092243,0.00007522227,0.003675118],"genre_scores_gemma":[0.9940132,0.0004163645,0.0006147938,0.00009007469,0.00001811781,0.000009360245,0.000132652,0.00003204785,0.004673377],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002410825,"threshold_uncertainty_score":0.008065045,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005741085937934185,"score_gpt":0.2083954426195077,"score_spread":0.2026543566815735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}