{"id":"W1977035059","doi":"10.1038/labinvest.2012.15","title":"Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells","year":2012,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"Population Health Research Institute; McMaster University; Health Sciences Centre","funders":"Novartis Institutes for BioMedical Research","keywords":"Mucin; Pathology; Macrophage; Tumor necrosis factor alpha; Goblet cell; Bronchus; Immunostaining; In vitro; Biology; Hyperplasia; Cytokine; CD68; Immunology; Lung; Epithelium; Immunohistochemistry; Medicine; Internal medicine; Respiratory disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002735899,0.0002201954,0.0002886644,0.0001788158,0.0001175777,0.00003199444,0.00007555891,0.0002148644,0.0000648221],"category_scores_gemma":[0.00006674019,0.0002208247,0.0000408444,0.0003934274,0.0001290144,0.0003039732,0.00004833367,0.0002988898,0.00009432841],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001456976,"about_ca_system_score_gemma":0.0001093683,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001028018,"about_ca_topic_score_gemma":0.000009944381,"domain_scores_codex":[0.9985715,0.0001334651,0.0003680713,0.0003132751,0.0002467079,0.0003670259],"domain_scores_gemma":[0.9989502,0.00003129721,0.000132948,0.0002464213,0.0001245515,0.0005145425],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002193637,0.0001212019,0.0380094,0.0001944254,0.00001132441,0.00004711188,0.001158544,0.00001500526,0.9587798,0.0003922574,0.0009715873,0.00007997896],"study_design_scores_gemma":[0.001434943,0.0009230311,0.2060701,0.0004170566,0.0001200156,0.00002183024,0.0009802565,0.000104306,0.7873619,0.0001123695,0.002047452,0.0004067371],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973465,0.0004442704,0.000004550444,0.0005679365,0.0003710166,0.0004424772,0.0002324607,0.00007110951,0.0005196411],"genre_scores_gemma":[0.9965848,0.00002091918,0.0003446583,0.002115609,0.0002836684,0.00003538485,0.0000779274,0.0000385764,0.0004984644],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1714179,"threshold_uncertainty_score":0.9004972,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01009027724075546,"score_gpt":0.2429642828167603,"score_spread":0.2328740055760049,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}