{"id":"W1977112375","doi":"10.1016/j.bbmt.2015.03.017","title":"The Sequence of Cyclophosphamide and Myeloablative Total Body Irradiation in Hematopoietic Cell Transplantation for Patients with Acute Leukemia","year":2015,"lang":"en","type":"article","venue":"Biology of Blood and Marrow Transplantation","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"National Cancer Institute; Office of Naval Research; National Heart, Lung, and Blood Institute; Onyx Pharmaceuticals; Terumo BCT; Health Resources and Services Administration; Medac; Swedish Orphan Biovitrum; Miltenyi Biotec; Incyte; Genentech; Seattle Genetics; Blue Cross and Blue Shield Association; Chimerix; Medical College of Wisconsin; Tarix Pharmaceuticals; StemCyte; University of Minnesota; Kiadis Pharma; Sigma-Tau Pharmaceuticals; Therakos; WellPoint; Teva Pharmaceutical Industries; HistoGenetics; University of Utah; St. Baldrick's Foundation; U.S. Department of Health and Human Services; Health Research; National Institute of Allergy and Infectious Diseases; Fred Hutchinson Cancer Research Center; Osiris Therapeutics; Celgene; Sanofi; Merck; GlaxoSmithKline; Allos Therapeutics; Actinium Pharmaceuticals; Ariad Pharmaceuticals; Otsuka America Pharmaceutical; Amgen; Leukemia and Lymphoma Society; Be The Match Foundation","keywords":"Medicine; Total body irradiation; Cyclophosphamide; Hematopoietic cell; Acute leukemia; Leukemia; Hematopoietic stem cell transplantation; Sequence (biology); Haematopoiesis; Transplantation; Bone marrow transplantation; Oncology; Internal medicine; Cancer research; Chemotherapy; Stem cell; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009732688,0.0001709786,0.0003518231,0.0002726322,0.0001995966,0.0003034486,0.0002255677,0.0002408412,0.0003822595],"category_scores_gemma":[0.002359333,0.00009713318,0.0002803884,0.0004239294,0.0002444583,0.0002417112,0.0002260771,0.0004171296,0.0001074534],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005216137,"about_ca_system_score_gemma":0.0008058897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009168704,"about_ca_topic_score_gemma":0.001844984,"domain_scores_codex":[0.9994605,0.0003008732,0.00005476862,0.00005180831,0.00009032903,0.00004171742],"domain_scores_gemma":[0.9990214,0.0003037305,0.0004091588,0.00004590677,0.0000323905,0.0001872931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02733468,0.001043359,0.8635498,0.0001421696,0.0003416353,0.0004145042,0.0001075993,0.00205675,0.006267526,0.0001096134,0.0004480653,0.09818426],"study_design_scores_gemma":[0.001460913,0.02534944,0.9645828,0.00005687386,0.0004219151,0.001668397,0.0001537394,0.002026018,0.002345918,0.0003354145,0.001583405,0.00001517372],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983815,0.001121479,0.000111836,0.00004935201,0.00001300808,0.00001905535,0.00003484834,0.000003198872,0.00026582],"genre_scores_gemma":[0.9990921,0.0004574257,0.000170355,0.00004657566,0.00002473884,0.0000185123,0.0001351046,0.000001157728,0.00005399379],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009732688,"threshold_uncertainty_score":0.005147219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009929580206526381,"score_gpt":0.2413152202382621,"score_spread":0.2313856400317358,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}