{"id":"W1977131009","doi":"10.1002/cyto.a.10063","title":"Immunoreactivity of Stat5 phosphorylated on tyrosine as a cell‐based measure of Bcr/Abl kinase activity","year":2003,"lang":"en","type":"article","venue":"Cytometry Part A","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"National Cancer Institute; National Institutes of Health","keywords":"Molecular biology; Flow cytometry; Imatinib mesylate; Biology; DAPI; ABL; Chronic myelogenous leukemia; Tyrosine kinase; STAT5; Chemistry; Leukemia; Cancer research; Cell biology; Phosphorylation; Immunology; Imatinib; Signal transduction; Myeloid leukemia; Biochemistry; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003543076,0.0004982924,0.0002529783,0.0007504877,0.0002631219,0.0002886653,0.000305298,0.0004605275,0.004713508],"category_scores_gemma":[0.0001274023,0.0001721357,0.0003086307,0.0004928957,0.0003090685,0.0003081506,0.0002344501,0.0005838108,0.0008828662],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003895151,"about_ca_system_score_gemma":0.0001371055,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002881531,"about_ca_topic_score_gemma":0.0004538861,"domain_scores_codex":[0.999676,0.00004865034,0.00002794268,0.00007430731,0.00010654,0.0000666666],"domain_scores_gemma":[0.999855,0.00003573527,0.00003380697,0.00001162735,0.00002951684,0.00003416615],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006647441,0.0000176257,0.0003547512,0.0000523635,0.000007136259,0.00001475867,0.00001186641,0.00002282268,0.998541,0.00008734506,0.00004160668,0.000782381],"study_design_scores_gemma":[0.00002024472,0.0002600823,0.01875572,0.00001646245,0.0000370177,0.0003378539,0.0000370034,0.001445993,0.9770181,0.00009565686,0.001968861,0.000007020695],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9499908,0.005827215,0.03524105,0.0001577844,0.000107506,0.0001098307,0.001407743,0.0002924274,0.006865659],"genre_scores_gemma":[0.9702293,0.002169778,0.02187521,0.0001172591,0.00004524402,0.0001648875,0.001871393,0.0000299253,0.003497078],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004713508,"threshold_uncertainty_score":0.01576823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02228093840885184,"score_gpt":0.2804245686566244,"score_spread":0.2581436302477725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}