{"id":"W1977164495","doi":"10.1038/labinvest.3700083","title":"A phosphorothioate antisense oligodeoxynucleotide specifically inhibits coxsackievirus B3 replication in cardiomyocytes and mouse hearts","year":2004,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of British Columbia and Yukon; Heart and Stroke Foundation of Canada","keywords":"Coxsackievirus; Capsid; Molecular biology; Viral replication; HeLa; Infectivity; Virology; RNA; Virus; Biology; Untranslated region; Titer; Transcription (linguistics); Transfection; Messenger RNA; Blot; Cell culture; Chemistry; Cell; Enterovirus; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004373888,0.0005432032,0.0004495284,0.0003326633,0.0002912737,0.0003502975,0.0003664066,0.0005466583,0.00157288],"category_scores_gemma":[0.000214455,0.0004131863,0.0003195827,0.0001609167,0.0004006453,0.0001811707,0.0001829506,0.0007339375,0.0003509543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000331766,"about_ca_system_score_gemma":0.0004654654,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001202533,"about_ca_topic_score_gemma":0.002621816,"domain_scores_codex":[0.9997231,0.00004714671,0.00002833726,0.00006946441,0.00004828414,0.00008360099],"domain_scores_gemma":[0.9996899,0.0001007876,0.00006477242,0.0000305852,0.00002448752,0.00008944886],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001782714,0.00001637699,0.00003896847,0.00002048635,0.00000424176,0.00001574779,0.000007048895,0.0000217641,0.999303,0.00006461195,0.00002440857,0.0003050969],"study_design_scores_gemma":[0.00008106713,0.0006566441,0.001032806,0.000005205869,0.00002661872,0.000088083,0.00001456828,0.000382681,0.9969432,0.00002903013,0.0007364111,0.000003797744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899943,0.001794313,0.00444446,0.0001737771,0.0001773562,0.00006192803,0.0002846593,0.0001988567,0.00287025],"genre_scores_gemma":[0.9860249,0.001424528,0.006085966,0.0001577276,0.0000900467,0.0001112226,0.0006360519,0.00007584189,0.00539369],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00157288,"threshold_uncertainty_score":0.005261779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02340313295585529,"score_gpt":0.280614075490476,"score_spread":0.2572109425346207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}