{"id":"W1977164495","doi":"10.1038/labinvest.3700083","title":"A phosphorothioate antisense oligodeoxynucleotide specifically inhibits coxsackievirus B3 replication in cardiomyocytes and mouse hearts","year":2004,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of British Columbia and Yukon; Heart and Stroke Foundation of Canada","keywords":"Coxsackievirus; Capsid; Molecular biology; Viral replication; HeLa; Infectivity; Virology; RNA; Virus; Biology; Untranslated region; Titer; Transcription (linguistics); Transfection; Messenger RNA; Blot; Cell culture; Chemistry; Cell; Enterovirus; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004648396,0.0001454773,0.000255877,0.0002252724,0.0001178844,0.0000487105,0.00004049449,0.0001555305,0.00001417885],"category_scores_gemma":[0.0003764437,0.00014409,0.00003182314,0.0007127768,0.0003442525,0.0002941956,0.00003404802,0.0003042547,0.00006420745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001811286,"about_ca_system_score_gemma":0.0002525438,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002660291,"about_ca_topic_score_gemma":0.00007052116,"domain_scores_codex":[0.9987249,0.000105068,0.0003294097,0.0004114977,0.0001886953,0.0002403905],"domain_scores_gemma":[0.9990356,0.00002309961,0.00007612577,0.0004625995,0.0002499937,0.0001525824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009319848,0.00008878685,0.07187476,0.00005585731,0.00003034747,0.00003852562,0.0004014618,0.00006397087,0.9234587,0.002067346,0.0002258534,0.001601207],"study_design_scores_gemma":[0.001794013,0.0002796754,0.2910868,0.0001504392,0.00002168471,0.00004759604,0.000094189,0.00009941026,0.7029568,0.0006578369,0.002647755,0.0001638468],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955204,0.0007944509,0.00003911228,0.002621914,0.00005540384,0.0005703128,0.00001471992,0.0001035842,0.0002801043],"genre_scores_gemma":[0.9972343,0.0007034414,0.0008916655,0.000880871,0.00005964798,0.00005561181,0.00004055823,0.00002582597,0.0001080434],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2205019,"threshold_uncertainty_score":0.5875818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02340313295585529,"score_gpt":0.280614075490476,"score_spread":0.2572109425346207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}