{"id":"W1977260469","doi":"10.1021/bi801302b","title":"Myelin Basic Protein as a “PI(4,5)P<sub>2</sub>-Modulin”: A New Biological Function for a Major Central Nervous System Protein","year":2008,"lang":"en","type":"article","venue":"Biochemistry","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; Hospital for Sick Children; University of Toronto","funders":"University of Toronto","keywords":"MARCKS; Myelin basic protein; Chemistry; Biochemistry; Phosphorylation; Citrullination; Myristoylation; Biophysics; Cell biology; Phosphocholine; Myelin; Membrane; Biology; Phospholipid; Phosphatidylcholine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000147609,0.0003713354,0.0002876414,0.00003390992,0.0002192405,0.00002701074,0.0002323446,0.0006513931,0.00002141623],"category_scores_gemma":[0.00007770959,0.0003539574,0.0003379466,0.0001261141,0.000118956,0.000006574482,0.00004805477,0.0001769466,0.00003127144],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000735621,"about_ca_system_score_gemma":0.0003817203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003919058,"about_ca_topic_score_gemma":0.0000095037,"domain_scores_codex":[0.9979517,0.00003845551,0.0004159614,0.0008063357,0.0002123004,0.0005752037],"domain_scores_gemma":[0.9989389,0.000005951756,0.0001623672,0.0004708073,0.0001174273,0.0003046003],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001134432,0.0001058436,0.0002526844,0.0002374307,0.00007319976,0.00002813784,0.00002529193,0.000005711558,0.996323,0.00005549927,0.0004102747,0.001348436],"study_design_scores_gemma":[0.001462522,0.0005242677,0.000746873,0.00009707166,0.00004287113,0.0001288119,0.00007337171,0.00008576544,0.9889654,0.00005025179,0.007374032,0.0004487921],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9728909,0.0008694917,0.02428495,0.0001234697,0.0001465118,0.001322719,0.00006198038,0.0001062536,0.0001937348],"genre_scores_gemma":[0.9919711,0.00003432345,0.0006948828,0.00007873368,0.001329668,0.0003874383,0.004118124,0.00005078089,0.001334925],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02359007,"threshold_uncertainty_score":0.9998912,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0113518753853036,"score_gpt":0.1953516401260059,"score_spread":0.1839997647407023,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}