{"id":"W1977362391","doi":"10.2147/ov.s59640","title":"The emerging therapeutic potential of the oncolytic immunotherapeutic Pexa-Vec (JX-594)","year":2015,"lang":"en","type":"review","venue":"Oncolytic Virotherapy","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Oncolytic virus; Vaccinia; Immunotherapy; Hepatocellular carcinoma; Cancer research; Cancer; Medicine; Immunology; Colorectal cancer; Immune system; Virotherapy; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007421272,0.0006782445,0.001137548,0.00009016421,0.0004346128,0.0001218164,0.001565089,0.0004278917,0.00007215247],"category_scores_gemma":[0.0000334753,0.0003667357,0.001160822,0.0004284779,0.0004954215,0.000007663897,0.0002456039,0.0004866508,0.00005014253],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003852884,"about_ca_system_score_gemma":0.002320965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001706897,"about_ca_topic_score_gemma":0.0001693335,"domain_scores_codex":[0.9963526,0.0006485826,0.0008127583,0.0006559133,0.0007887571,0.0007414325],"domain_scores_gemma":[0.9971417,0.00008857073,0.000641968,0.001803953,0.0001645415,0.0001592561],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001875051,0.0001880834,0.000009204841,0.0004884804,0.001645567,0.000005887856,0.00005226134,0.000005545118,0.001010728,0.00005257099,0.0009960097,0.9953582],"study_design_scores_gemma":[0.001423512,0.000667788,0.00001530236,0.0008555008,0.0005433936,0.00006802821,0.0000447942,0.00001556277,0.0003002045,0.0001733144,0.9955098,0.000382771],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002144385,0.9953862,0.00009444964,0.0001734105,0.0006413936,0.00238871,0.00007754922,0.0000178334,0.001006002],"genre_scores_gemma":[0.001769494,0.991357,0.00002408594,0.0001821182,0.0005620672,0.0005462482,0.00006002665,0.0001827146,0.005316249],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9949754,"threshold_uncertainty_score":0.9998785,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03707615220644535,"score_gpt":0.3786682573576426,"score_spread":0.3415921051511973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}