{"id":"W1977362391","doi":"10.2147/ov.s59640","title":"The emerging therapeutic potential of the oncolytic immunotherapeutic Pexa-Vec (JX-594)","year":2015,"lang":"en","type":"review","venue":"Oncolytic Virotherapy","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Oncolytic virus; Vaccinia; Immunotherapy; Hepatocellular carcinoma; Cancer research; Cancer; Medicine; Immunology; Colorectal cancer; Immune system; Virotherapy; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003020571,0.0004808526,0.0006213153,0.001612019,0.0001770646,0.0007214008,0.0003727216,0.0007649296,0.002709818],"category_scores_gemma":[0.0003057856,0.0002047982,0.0003879945,0.001052468,0.0002697972,0.0009181512,0.0004552013,0.001485638,0.001218147],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004389374,"about_ca_system_score_gemma":0.0006199214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005717875,"about_ca_topic_score_gemma":0.0009442735,"domain_scores_codex":[0.9999056,0.00001267383,0.00001125076,0.00001948499,0.00003809013,0.0000128868],"domain_scores_gemma":[0.9998859,0.00005112735,0.0000164325,0.000003336571,0.00002983899,0.00001333312],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006489007,0.00007004596,0.0001623811,0.01267584,0.00006141477,0.0002247563,0.00006354298,0.0004235611,0.008864796,0.004658231,0.0189055,0.9538252],"study_design_scores_gemma":[0.00001137225,0.0001068168,0.0005144734,0.001115606,0.00006818771,0.001285684,0.00003057295,0.00008454829,0.001957465,0.001130388,0.9936814,0.00001348173],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003909877,0.9970554,0.0003131979,0.0002467957,0.0001671785,0.000006077988,0.00003065497,0.00001069531,0.001779092],"genre_scores_gemma":[0.002024964,0.996005,0.0003740891,0.0002590646,0.0001103956,0.000009913457,0.00005999043,0.000002633823,0.001154063],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002709818,"threshold_uncertainty_score":0.009065211,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03707615220644535,"score_gpt":0.3786682573576426,"score_spread":0.3415921051511973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}