{"id":"W1977461498","doi":"10.1021/bi025835w","title":"Role of Tyrosine-103 in Myoglobin Peroxidase Activity:  Kinetic and Steady-State Studies on the Reaction of Wild-Type and Variant Recombinant Human Myoglobins with H<sub>2</sub>O<sub>2</sub>","year":2002,"lang":"en","type":"article","venue":"Biochemistry","topic":"Hemoglobin structure and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; Myoglobin; Thioanisole; Peroxidase; Heme; Electron transfer; Globin; Hemeprotein; Reaction rate constant; Stereochemistry; Enzyme; Biochemistry; Hemoglobin; Kinetics; Photochemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002487905,0.000227588,0.0002576144,0.00005537966,0.00009346099,0.0003316664,0.0002640341,0.0003191607,0.0006010159],"category_scores_gemma":[0.0003724345,0.0001078335,0.0001849846,0.0001132252,0.0002521418,0.0002277304,0.0001098874,0.0005282288,0.0002003341],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004126175,"about_ca_system_score_gemma":0.0001564459,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007203831,"about_ca_topic_score_gemma":0.0004503997,"domain_scores_codex":[0.9998628,0.00002547259,0.00001194291,0.0000348592,0.00003908243,0.00002589202],"domain_scores_gemma":[0.9997795,0.00006396763,0.00007170508,0.0000185194,0.00003376574,0.00003253746],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000202122,0.00004681853,0.0008022772,0.00002859417,0.000006627823,0.00003474851,0.00003971808,0.00007044964,0.9975057,0.0001175947,0.00001476658,0.001130523],"study_design_scores_gemma":[0.00001835261,0.0002689935,0.008120993,0.00000481547,0.00001289677,0.00019653,0.00003163701,0.003097017,0.9878165,0.00006184268,0.0003648998,0.000005441094],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997726,0.000275179,0.001715455,0.00002710428,0.000006706989,0.000006631386,0.00004867617,0.0000186825,0.0001757273],"genre_scores_gemma":[0.9985501,0.00008329657,0.0008879742,0.00001546808,0.00000213821,0.00000700814,0.0001232309,0.00001177153,0.0003190043],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007203831,"threshold_uncertainty_score":0.002993703,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01181614215041804,"score_gpt":0.2199475718616365,"score_spread":0.2081314297112185,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}