{"id":"W1977461498","doi":"10.1021/bi025835w","title":"Role of Tyrosine-103 in Myoglobin Peroxidase Activity:  Kinetic and Steady-State Studies on the Reaction of Wild-Type and Variant Recombinant Human Myoglobins with H<sub>2</sub>O<sub>2</sub>","year":2002,"lang":"en","type":"article","venue":"Biochemistry","topic":"Hemoglobin structure and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; Myoglobin; Thioanisole; Peroxidase; Heme; Electron transfer; Globin; Hemeprotein; Reaction rate constant; Stereochemistry; Enzyme; Biochemistry; Hemoglobin; Kinetics; Photochemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002079764,0.0002981763,0.0003410698,0.0000568696,0.0001005123,0.00001822746,0.0001055528,0.0002118829,0.000002095372],"category_scores_gemma":[0.0001091321,0.0002239864,0.00005052701,0.0002324208,0.0003014586,0.00001182544,0.0000993059,0.0001991867,9.530564e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004293244,"about_ca_system_score_gemma":0.00004233918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002517922,"about_ca_topic_score_gemma":0.00002655168,"domain_scores_codex":[0.9986384,0.00007647696,0.0003313185,0.0005108895,0.0001860594,0.0002568534],"domain_scores_gemma":[0.9990137,0.00003500186,0.0002747123,0.0004393935,0.0001587548,0.00007838997],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002962597,0.0001679767,0.0005517379,0.0001354219,0.0001092208,0.00000610725,0.0002048657,0.000009813718,0.9935884,0.00002047938,0.000238998,0.004670659],"study_design_scores_gemma":[0.0008550445,0.0007505112,0.005127606,0.0001624107,0.0000621197,0.00006866764,0.0004150361,0.00004022799,0.9921018,0.00008306535,0.00008624478,0.0002472404],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980341,0.001318047,0.000005137128,0.00009684403,0.00007875784,0.0002512011,0.00002525802,0.0000110627,0.0001796188],"genre_scores_gemma":[0.9984158,0.001323794,0.00002273514,0.00004419133,0.00006774063,0.00002090645,0.00003438158,0.00002741868,0.00004300159],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004575868,"threshold_uncertainty_score":0.9133902,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01181614215041804,"score_gpt":0.2199475718616365,"score_spread":0.2081314297112185,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}