{"id":"W1977467032","doi":"10.1021/bi901512b","title":"Kinetic Studies of HPr, HPr(H15D), HPr(H15E), and HPr(His∼P) Phosphorylation by the <i>Streptococcus salivarius</i> HPr(Ser) Kinase/Phosphorylase","year":2009,"lang":"en","type":"article","venue":"Biochemistry","topic":"Streptococcal Infections and Treatments","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"PROTEO; Université Laval","funders":"Canadian Institutes of Health Research","keywords":"PEP group translocation; Phosphorylation; Chemistry; Kinase; Enzyme kinetics; Enzyme; Phosphotransferase; Stereochemistry; Glycogen phosphorylase; Biochemistry; Phosphoenolpyruvate carboxykinase; Molecular biology; Biology; Active site","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005964109,0.0005361859,0.0006283614,0.00019859,0.0001383705,0.0003137866,0.000419884,0.0003021712,0.001004013],"category_scores_gemma":[0.0005115308,0.0002122841,0.0005465379,0.0003692667,0.0001990571,0.0003781508,0.0002280461,0.0005640408,0.0007869374],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005162678,"about_ca_system_score_gemma":0.0002153188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002104088,"about_ca_topic_score_gemma":0.00119742,"domain_scores_codex":[0.9995147,0.0001272557,0.00004515867,0.00009864031,0.0001135967,0.0001007576],"domain_scores_gemma":[0.9995844,0.0001424277,0.00008519147,0.00003143838,0.00008231032,0.00007422656],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001182233,0.0002305528,0.002090537,0.0003034174,0.00008287362,0.0001201726,0.0001410371,0.003122602,0.9839593,0.0003068139,0.0002142658,0.008246072],"study_design_scores_gemma":[0.00003057135,0.0007845435,0.006381601,0.00001318943,0.00003629504,0.0002375507,0.000074527,0.01410685,0.9766672,0.00005582432,0.001573653,0.0000381305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890886,0.004025137,0.004287225,0.00006866298,0.00003664233,0.00004005925,0.0005977649,0.00008355851,0.001772236],"genre_scores_gemma":[0.9900846,0.001755616,0.005132945,0.00002280795,0.00001185407,0.00003120398,0.0010098,0.00004516866,0.001906001],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002104088,"threshold_uncertainty_score":0.00418371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01651144696542815,"score_gpt":0.295091006193062,"score_spread":0.2785795592276338,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}