{"id":"W1977481910","doi":"10.1074/jbc.m700899200","title":"Characterization of Pancreatic Transcription Factor Pdx-1 Binding Sites Using Promoter Microarray and Serial Analysis of Chromatin Occupancy","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":104,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Transcription factor; Chromatin; Microarray; Occupancy; Chromatin immunoprecipitation; Microarray analysis techniques; Transcription (linguistics); Biology; Promoter; Computational biology; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000204791,0.0002645613,0.0003423498,0.0004247332,0.000208266,0.0003138189,0.0002039212,0.0001630626,0.0013299],"category_scores_gemma":[0.0002934075,0.0002813897,0.0002836193,0.00039312,0.0001826886,0.0001547282,0.0001887939,0.0005726279,0.0004653607],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003285269,"about_ca_system_score_gemma":0.0002354351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009001379,"about_ca_topic_score_gemma":0.002637207,"domain_scores_codex":[0.9996661,0.00003165939,0.00001464917,0.0001309119,0.00009988235,0.00005684399],"domain_scores_gemma":[0.9998021,0.00008102126,0.00003897041,0.00001853597,0.00002848544,0.00003098769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005426443,0.00001539518,0.0008968635,0.00001869932,0.000004901072,0.000007180349,0.00001764064,0.0001082745,0.9969676,0.00005370107,0.000024121,0.001831301],"study_design_scores_gemma":[0.00001918949,0.0001769628,0.04373465,0.000007469271,0.00003607898,0.0001630637,0.00004615523,0.006066019,0.947277,0.0001433539,0.002313791,0.00001616947],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9623762,0.001091271,0.03250731,0.0001166936,0.00002160329,0.00005284128,0.002383721,0.0001512391,0.001299165],"genre_scores_gemma":[0.9290625,0.0009397301,0.05785849,0.000148814,0.00002806145,0.0002221026,0.008001323,0.00007681907,0.003662019],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0013299,"threshold_uncertainty_score":0.00444895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03808714492098862,"score_gpt":0.2788948934146199,"score_spread":0.2408077484936313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}