{"id":"W1977504617","doi":"10.1006/mthe.2001.0314","title":"Regulated Expression of the Human CFTR Gene in Epithelial Cells","year":2001,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"","keywords":"Doxycycline; Cystic fibrosis transmembrane conductance regulator; Biology; Molecular biology; Gene expression; Transfection; Immunostaining; Cell culture; Transgene; Epithelium; Transactivation; Cell biology; Cystic fibrosis; Gene; Immunohistochemistry; Immunology; Microbiology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033308,0.000200464,0.0003204516,0.0003384039,0.0001826158,0.000547889,0.0001625701,0.0004034492,0.001124782],"category_scores_gemma":[0.0003822546,0.0001260258,0.0003830376,0.0001992551,0.0004530619,0.0002621553,0.0002481056,0.0006989567,0.0005572384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005915259,"about_ca_system_score_gemma":0.0003179947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006802424,"about_ca_topic_score_gemma":0.0006234923,"domain_scores_codex":[0.9995456,0.000141777,0.00003518062,0.00007992284,0.0001105831,0.00008692686],"domain_scores_gemma":[0.9997119,0.0001265475,0.00002766096,0.00006030813,0.00004799122,0.00002553914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007581329,0.00001182835,0.00005028004,0.00001285844,0.000001530935,0.00003548265,0.00001782025,0.00003412802,0.9987411,0.0002873705,0.00005032556,0.0006813771],"study_design_scores_gemma":[0.00001146213,0.00009434042,0.001140519,0.000005798882,0.000005349053,0.000149381,0.00003263232,0.0005976253,0.9955019,0.00008646116,0.002370884,0.000003608586],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9779804,0.005512769,0.009719773,0.0005209657,0.0001973648,0.00006870891,0.0008005216,0.0002009903,0.00499843],"genre_scores_gemma":[0.9886285,0.001117922,0.004061682,0.0001260591,0.00002335815,0.00003293956,0.0009594843,0.00005805642,0.004992018],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001124782,"threshold_uncertainty_score":0.004291892,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01496551292999015,"score_gpt":0.3017647794008448,"score_spread":0.2867992664708547,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}