{"id":"W1977542592","doi":"10.1371/journal.pone.0078280","title":"Evidence for a Retroviral Insertion in TRPM1 as the Cause of Congenital Stationary Night Blindness and Leopard Complex Spotting in the Horse","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":185,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; University of Saskatchewan; Deutsche Forschungsgemeinschaft; University of Tampa; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Cancer Institute; National Institutes of Health; National Science Foundation","keywords":"Biology; Genetics; Transposable element; Endogenous retrovirus; Exon; Insertion; Gene; Mutation; Mutant; Genome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002491267,0.00005196021,0.00007130961,0.00002476595,0.00003384301,0.00001638111,0.00007984857,0.00003853874,0.00001217128],"category_scores_gemma":[0.0002191246,0.00003514547,0.00001406508,0.00005717564,0.00004519599,0.00001133243,0.00002107109,0.00004304051,0.00000154354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006892732,"about_ca_system_score_gemma":0.00002005569,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001306157,"about_ca_topic_score_gemma":0.0001580004,"domain_scores_codex":[0.999447,0.00009668223,0.0001577565,0.0001119221,0.0001051339,0.00008150468],"domain_scores_gemma":[0.9996915,0.0000923578,0.00005929672,0.00008974759,0.00005506697,0.00001204053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001665735,0.0002135474,0.06281351,0.00004663174,0.00002856241,8.293213e-7,0.001145449,0.000005366192,0.9348198,0.0000797527,0.0001011843,0.0005787915],"study_design_scores_gemma":[0.001524581,0.0007849755,0.7588465,0.0001420272,0.00005361245,0.000006425013,0.002508589,0.002508684,0.2327459,0.0007052983,0.00002614167,0.0001472625],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986264,0.0002570389,0.00003599271,0.0004517205,0.000009481115,0.0005422445,0.000007140258,0.00000145593,0.00006858932],"genre_scores_gemma":[0.9990386,0.00009950461,0.0003779518,0.0002016483,0.0000397437,0.0001214442,0.00005892485,0.000004591093,0.00005759199],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7020739,"threshold_uncertainty_score":0.1433191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1411215303866015,"score_gpt":0.3116858498107884,"score_spread":0.1705643194241869,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}