{"id":"W1977566571","doi":"10.1016/j.thromres.2011.02.019","title":"Genetic determinants of response to aspirin: Appraisal of 4 candidate genes","year":2011,"lang":"en","type":"article","venue":"Thrombosis Research","topic":"Antiplatelet Therapy and Cardiovascular Diseases","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôtel-Dieu de Montréal; Hôpital du Sacré-Cœur de Montréal; Université de Montréal","funders":"Canadian Institutes of Health Research; Chinese Academy of Agricultural Sciences","keywords":"Aspirin; Arachidonic acid; Platelet; Platelet activation; Pharmacology; Adenosine diphosphate; Cyclooxygenase; Genotype; Platelet-poor plasma; Medicine; Internal medicine; Chemistry; Gene; Biochemistry; Platelet aggregation; Thrombin; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001433115,0.0001135335,0.0004869967,0.000334854,0.00005795047,0.000004623037,0.0002365864,0.00007998498,0.0004582112],"category_scores_gemma":[0.0002768205,0.00009505115,0.0002226776,0.0004986724,0.000323814,0.00003733559,0.0001329724,0.000126872,0.00007182044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002326369,"about_ca_system_score_gemma":0.0002461454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005469762,"about_ca_topic_score_gemma":0.00002800045,"domain_scores_codex":[0.9977822,0.0004627494,0.0003188413,0.0002587716,0.0008032352,0.0003742457],"domain_scores_gemma":[0.9984762,0.0001889709,0.00004764485,0.0006810543,0.0003703087,0.0002357869],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01212693,0.0007605136,0.5151479,0.0005555444,0.0007166271,0.0001552292,0.002540818,0.000004500763,0.3878014,0.00003298213,0.0004420418,0.07971542],"study_design_scores_gemma":[0.0008017511,0.001102763,0.7347968,0.000142092,0.00006295658,0.00001815648,0.0002474663,0.00001266945,0.2617649,0.00002287392,0.0009525271,0.00007504779],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973039,0.001298929,0.00006155227,0.00003595089,0.000048399,0.0004095618,0.00002203813,0.000015808,0.0008038423],"genre_scores_gemma":[0.9982845,0.0005915331,0.0008780238,0.00002247147,0.00004678514,0.00003181622,0.0000020403,0.00002715049,0.0001156354],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2196488,"threshold_uncertainty_score":0.5017091,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.133784596104803,"score_gpt":0.419411046074028,"score_spread":0.285626449969225,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}