{"id":"W1977595014","doi":"10.1016/j.lfs.2005.09.016","title":"Tissue distribution and induction of the rat multidrug resistance-associated proteins 5 and 6","year":2005,"lang":"en","type":"article","venue":"Life Sciences","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; Ryerson University","keywords":"Cholestasis; Biology; Multidrug resistance-associated protein 2; Endocrinology; Internal medicine; Kidney; Bile duct; Transporter; ATP-binding cassette transporter; Biochemistry; Medicine; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002422437,0.0004044836,0.0003450418,0.0008131403,0.0002269488,0.000447907,0.0002232854,0.0003960095,0.00238353],"category_scores_gemma":[0.000313073,0.0003362547,0.0005263381,0.0003334526,0.0004658885,0.0005868546,0.0002096479,0.001053318,0.0008902],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005125617,"about_ca_system_score_gemma":0.0003555649,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008447728,"about_ca_topic_score_gemma":0.000858559,"domain_scores_codex":[0.9997925,0.00003556807,0.00001205751,0.00005193145,0.00003462024,0.00007338624],"domain_scores_gemma":[0.9994991,0.00009690895,0.0001610929,0.00006173669,0.00007164245,0.0001095635],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001025935,0.00005671725,0.0006811817,0.00004894684,0.00002145593,0.0001125939,0.00005064507,0.0000604101,0.99462,0.0004893907,0.00009231835,0.002740391],"study_design_scores_gemma":[0.0000350018,0.001233134,0.02016118,0.000009720641,0.00009478187,0.0005604204,0.000118763,0.0006528532,0.9747773,0.000196642,0.002146933,0.00001331772],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9843708,0.004780682,0.006400308,0.0002832607,0.00007363481,0.00002834857,0.0007190173,0.0001926051,0.003151323],"genre_scores_gemma":[0.9833558,0.002513994,0.002652537,0.00006519703,0.00003088275,0.00004589053,0.001557378,0.00005238084,0.009726109],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00238353,"threshold_uncertainty_score":0.007973731,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01377991278708466,"score_gpt":0.2538607957071599,"score_spread":0.2400808829200753,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}