{"id":"W1977595953","doi":"10.1091/mbc.12.12.3852","title":"TGFβ and PTHrP Control Chondrocyte Proliferation by Activating Cyclin D1 Expression","year":2001,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":137,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Cancer Institute; Medical Research Council Canada; Fondation pour la Recherche Médicale; Deutsche Forschungsgemeinschaft; Arthritis Society; Medical Research Council; Deutscher Akademischer Austauschdienst; Alberta Cancer Foundation","keywords":"Cyclin D1; Cyclin D; Biology; Cyclin A; Chondrocyte; Cell biology; Cyclin B; Cyclin A2; Cyclin; Cancer research; Transcription factor; Cell growth; Cyclin E; Cell cycle; Molecular biology; Gene; Genetics; Anatomy; Cartilage","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006415189,0.0001910613,0.00009928405,0.0002494893,0.0001625439,0.0003198351,0.0001167421,0.0001412249,0.001053314],"category_scores_gemma":[0.0001388738,0.0001192046,0.0001035252,0.0001059746,0.0002209699,0.0001144336,0.0001545314,0.0002357518,0.0002958211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003089513,"about_ca_system_score_gemma":0.0002404165,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000865571,"about_ca_topic_score_gemma":0.001494478,"domain_scores_codex":[0.9999386,0.000006934669,0.000004052045,0.00001498551,0.00001772655,0.00001768683],"domain_scores_gemma":[0.9999336,0.00001193894,0.0000222357,0.000005454245,0.000009003676,0.00001767307],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001585392,0.00001341056,0.0009459755,0.00006154972,0.000004227344,0.00008530188,0.00002934353,0.00008377158,0.9911976,0.0005177525,0.0001217143,0.006780705],"study_design_scores_gemma":[0.00005952466,0.0002182702,0.01626647,0.00001262619,0.00001553107,0.0006066494,0.00006762998,0.0008800215,0.9633818,0.0004567634,0.01802814,0.000006610855],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9636666,0.0184247,0.007623237,0.0004300976,0.00007641127,0.00004597849,0.0006097958,0.0001655138,0.008957641],"genre_scores_gemma":[0.9870704,0.005688355,0.003124763,0.00004982527,0.00002293321,0.00002352672,0.0002875911,0.00002089268,0.003711775],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001053314,"threshold_uncertainty_score":0.003523648,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004970003678309032,"score_gpt":0.2383899207137823,"score_spread":0.2334199170354733,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}