{"id":"W1977595953","doi":"10.1091/mbc.12.12.3852","title":"TGFβ and PTHrP Control Chondrocyte Proliferation by Activating Cyclin D1 Expression","year":2001,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":137,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Cancer Institute; Medical Research Council Canada; Fondation pour la Recherche Médicale; Deutsche Forschungsgemeinschaft; Arthritis Society; Medical Research Council; Deutscher Akademischer Austauschdienst; Alberta Cancer Foundation","keywords":"Cyclin D1; Cyclin D; Biology; Cyclin A; Chondrocyte; Cell biology; Cyclin B; Cyclin A2; Cyclin; Cancer research; Transcription factor; Cell growth; Cyclin E; Cell cycle; Molecular biology; Gene; Genetics; Anatomy; Cartilage","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001421272,0.0001464506,0.0002557908,0.00004723055,0.00007583461,0.000005482765,0.0001019501,0.0002160873,0.00002141132],"category_scores_gemma":[0.0001111118,0.0001050639,0.00009426545,0.0001068166,0.0001335528,0.00002205013,0.00006356393,0.0002404356,0.000004085021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003665018,"about_ca_system_score_gemma":0.00004675624,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001755203,"about_ca_topic_score_gemma":0.000001489929,"domain_scores_codex":[0.99902,0.0001510434,0.0002390405,0.000271889,0.0001128937,0.0002050864],"domain_scores_gemma":[0.9993299,0.00003492355,0.0001771641,0.0003357684,0.0000553459,0.00006688647],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001629265,0.00006561404,0.002938939,0.00002523925,0.00002987194,0.000008379,0.00005866995,0.00003814986,0.9949534,0.00001624586,0.0004334062,0.001269191],"study_design_scores_gemma":[0.00264826,0.0002027459,0.0004712393,0.00008004541,0.00005865201,0.00005476414,0.00001743082,0.0004443207,0.9917782,0.0001293764,0.004016161,0.00009881858],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9771373,0.002708649,0.01721265,0.00107218,0.0001757689,0.0005751278,0.000009961531,0.00002799951,0.001080408],"genre_scores_gemma":[0.9980993,0.0001109841,0.0006295122,0.0007403389,0.00003732829,0.00002360359,0.00002730009,0.00002292045,0.0003087703],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02096198,"threshold_uncertainty_score":0.4284383,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004970003678309032,"score_gpt":0.2383899207137823,"score_spread":0.2334199170354733,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}