{"id":"W1977610810","doi":"10.1128/jvi.02322-09","title":"Broad-Spectrum<i>In Vitro</i>Activity and<i>In Vivo</i>Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family<i>Coronaviridae</i>","year":2009,"lang":"en","type":"article","venue":"Journal of Virology","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":304,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; U.S. Public Health Service; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Coronaviridae; Biology; Virology; Coronavirus; In vivo; Antiviral protein; Virus; Outbreak; Immunology; RNA; Disease; Infectious disease (medical specialty); Genetics; Coronavirus disease 2019 (COVID-19); Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009465811,0.000199243,0.0007244002,0.0002987395,0.00005626207,0.000008954543,0.000411691,0.0001644578,0.000002901527],"category_scores_gemma":[0.0003458962,0.0001179276,0.0002742264,0.0005914572,0.0003793632,0.0001382794,0.0001205927,0.001004202,8.771835e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001027076,"about_ca_system_score_gemma":0.0003539533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001952259,"about_ca_topic_score_gemma":0.0001132647,"domain_scores_codex":[0.9976397,0.0004486905,0.0007475702,0.0002179652,0.0005426806,0.0004034114],"domain_scores_gemma":[0.9986844,0.0002140547,0.0005952438,0.000385441,0.00008664926,0.00003417803],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003510656,0.0006753464,0.05054683,0.00003627229,0.00003785398,0.00007178994,0.0002513672,0.00001443336,0.9374986,0.00003899376,0.00003442665,0.007283463],"study_design_scores_gemma":[0.002827254,0.0004879332,0.3782524,0.0001680965,0.0000269718,0.00006891007,0.00004665018,0.0001130948,0.6165725,0.0001881032,0.001179112,0.0000689216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953119,0.0008340929,0.00002185188,0.002604513,0.0001320032,0.0004788212,0.000006000019,0.00000521329,0.0006055775],"genre_scores_gemma":[0.9897776,0.00004665463,0.00005789132,0.009976178,0.0001138973,0.000003247704,5.413461e-8,0.0000159567,0.000008512844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3277056,"threshold_uncertainty_score":0.4808947,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02366587066854521,"score_gpt":0.3187050586065835,"score_spread":0.2950391879380383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}