{"id":"W1977623088","doi":"10.1016/j.joca.2013.05.004","title":"Inflammatory stimuli differentially modulate the transcription of paracrine signaling molecules of equine bone marrow multipotent mesenchymal stromal cells","year":2013,"lang":"en","type":"article","venue":"Osteoarthritis and Cartilage","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"Canadian Arthritis Network","keywords":"Paracrine signalling; Mesenchymal stem cell; Stromal cell; Bone marrow; Cell biology; Tumor necrosis factor alpha; Cancer research; Inflammation; Autocrine signalling; Medicine; Immunology; Biology; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000212594,0.0002933197,0.0003070725,0.0004451028,0.0002179233,0.0004950131,0.0000863038,0.0001760463,0.002946565],"category_scores_gemma":[0.0002372522,0.0001254279,0.0002387893,0.0002012815,0.0002729248,0.0002552083,0.0003202745,0.0004537816,0.0003655081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002176897,"about_ca_system_score_gemma":0.0002546672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004874485,"about_ca_topic_score_gemma":0.00150187,"domain_scores_codex":[0.9996873,0.00005996633,0.000031966,0.00004012319,0.00007671177,0.0001039031],"domain_scores_gemma":[0.9998502,0.00003998662,0.00002929051,0.00001002993,0.00002923308,0.00004126537],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006584049,0.0000476885,0.0009559948,0.00008149074,0.000006416941,0.0001171976,0.00008262135,0.00003446066,0.9951034,0.0001608525,0.00006728313,0.00268426],"study_design_scores_gemma":[0.00007431849,0.0009650355,0.0638293,0.00004612147,0.0000616484,0.0004490818,0.000823544,0.0007016239,0.9255582,0.0002017439,0.007275518,0.00001382859],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917399,0.004409777,0.0008772499,0.0001253399,0.00005747242,0.00002854753,0.0004215766,0.00001850164,0.002321749],"genre_scores_gemma":[0.9924728,0.0016332,0.000751777,0.0001393088,0.00004143172,0.00005632617,0.0006105601,0.00001169793,0.004282929],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002946565,"threshold_uncertainty_score":0.009857237,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009912614618948715,"score_gpt":0.2116346426172548,"score_spread":0.2017220279983061,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}