{"id":"W1977656313","doi":"10.1016/j.humpath.2007.09.021","title":"Membrane-type-1 matrix metalloproteinase, matrix metalloproteinase 2, and tissue inhibitor of matrix proteinase 2 in prostate cancer: identification of patients with poor prognosis by immunohistochemistry","year":2008,"lang":"en","type":"article","venue":"Human Pathology","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre hospitalier universitaire de Québec; Université Laval","funders":"","keywords":"Stromal cell; Immunohistochemistry; Matrix metalloproteinase; Prostate cancer; MMP2; Hazard ratio; Cancer research; Prostate; Cancer; Medicine; Oncology; Chemistry; Pathology; Internal medicine; Metastasis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00032788,0.0003660446,0.0005672124,0.000157443,0.0001289232,0.00001174694,0.0002528003,0.0002848301,0.00003920626],"category_scores_gemma":[0.00007402775,0.0003435229,0.00008234476,0.0002521868,0.0004138792,0.00003068913,0.0001578547,0.0001944219,0.000002826766],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003980119,"about_ca_system_score_gemma":0.0001402143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001622399,"about_ca_topic_score_gemma":0.00001699672,"domain_scores_codex":[0.9976021,0.0001595919,0.0008513016,0.000705076,0.0002999963,0.0003819128],"domain_scores_gemma":[0.9983544,0.000007347868,0.0006965032,0.000489487,0.0003500878,0.0001022147],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007194506,0.0005148738,0.003145737,0.000474454,0.00006445403,0.00004969873,0.0001225524,0.000007392119,0.9945828,0.00005037013,0.0001032226,0.0001649717],"study_design_scores_gemma":[0.002291462,0.00139328,0.001027714,0.00008281513,0.00007587184,0.00004293942,0.00003983916,0.00000493931,0.9942791,0.00004679381,0.0003602058,0.0003550652],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924893,0.004607303,0.00005768353,0.00003903931,0.00005679794,0.002401526,0.0003049359,0.00002029593,0.00002311262],"genre_scores_gemma":[0.9960687,0.0002648061,0.001001255,0.00001451078,0.00004796346,0.0008219154,0.0006099621,0.00005986383,0.001111052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004342497,"threshold_uncertainty_score":0.9999017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005737236236752796,"score_gpt":0.2554802820113122,"score_spread":0.2497430457745594,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}