{"id":"W1977658329","doi":"10.1139/o06-209","title":"Staurosporine inhibition of zipper-interacting protein kinase contractile effects in gastrointestinal smooth muscle","year":2007,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Myosin light-chain kinase; Myosin; Biology; Protein kinase A; Rho-associated protein kinase; Staurosporine; Protein kinase C; Phosphorylation; Cell biology; Kinase; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003418572,0.0001596876,0.0001687555,0.0000468625,0.00004040034,0.000006985852,0.00005801641,0.0001544334,0.00001806999],"category_scores_gemma":[0.0001753294,0.0001609487,0.00005191319,0.00007828897,0.0001160431,0.000004720744,0.00006458302,0.0001334675,9.343723e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001633965,"about_ca_system_score_gemma":0.00004226276,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003260459,"about_ca_topic_score_gemma":0.00001070759,"domain_scores_codex":[0.9989877,0.00004284608,0.0003058803,0.0003372795,0.0000547425,0.000271555],"domain_scores_gemma":[0.9994728,0.00003922343,0.0001794949,0.0001635989,0.00005903402,0.00008582204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002339962,0.0001158213,0.003042016,0.0001636177,0.000003324323,0.00002623196,0.00001121716,0.000005282381,0.9914276,0.00005018604,0.000008134549,0.004912564],"study_design_scores_gemma":[0.0009283681,0.0002668349,0.003378143,0.0001714752,0.00000481801,0.00001902919,0.00008133042,0.00003848074,0.9937972,0.00005437007,0.001104822,0.0001551236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957604,0.0006770696,0.002298814,0.00002262042,0.00002989126,0.0002294183,0.00001228881,0.00001009557,0.0009594061],"genre_scores_gemma":[0.9979483,0.0000110636,0.001590144,0.00003654591,0.0001207801,0.0000147377,0.0001450852,0.00001171321,0.0001215955],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00475744,"threshold_uncertainty_score":0.6563298,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00564783236817217,"score_gpt":0.2311960741339134,"score_spread":0.2255482417657413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}