{"id":"W1977749822","doi":"10.1016/s0306-4522(02)00376-7","title":"Immunohistochemical and biochemical assessment of caspase-3 activation and DNA fragmentation following transient focal ischemia in the rat","year":2002,"lang":"en","type":"article","venue":"Neuroscience","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":130,"is_retracted":false,"has_abstract":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"TUNEL assay; DNA fragmentation; In Situ Nick-End Labeling; NeuN; Molecular biology; Caspase 3; Biology; Ischemia; Fragmentation (computing); Programmed cell death; Apoptosis; Pathology; Cell biology; Chemistry; Immunohistochemistry; Biochemistry; Medicine; Internal medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001228522,0.00006541006,0.00006037874,0.00002350438,0.00005826391,0.00001595125,0.00006664546,0.00005525113,0.000001786447],"category_scores_gemma":[0.00002775909,0.00005073704,0.00002435438,0.00009105556,0.00008930576,0.000008781765,0.00002655026,0.00005771052,4.664586e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008117502,"about_ca_system_score_gemma":0.000008319392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004898135,"about_ca_topic_score_gemma":7.481147e-7,"domain_scores_codex":[0.9994061,0.000028547,0.0001185788,0.0002152507,0.0001395757,0.00009197195],"domain_scores_gemma":[0.9998118,0.00001342293,0.00003755123,0.000104258,0.00001019344,0.00002273878],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000004730402,0.00003459712,0.0004098746,0.000006346871,6.57881e-7,8.114353e-7,0.0001010808,0.00001437197,0.9984206,0.00006113981,0.00004550983,0.0009003126],"study_design_scores_gemma":[0.0003763523,0.0001341724,0.01766566,0.00001176329,0.00000692181,0.00001443985,0.00007183534,0.005978817,0.9753209,0.00002550843,0.0003196689,0.00007397221],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964156,0.0001499354,0.002918459,0.0002035272,0.00006129933,0.0001318243,9.317259e-7,0.000002130073,0.0001162861],"genre_scores_gemma":[0.9993429,0.00008656839,0.000352006,0.0001626018,0.00001490068,0.00001001026,0.000007460681,0.000003660075,0.00001990806],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02309968,"threshold_uncertainty_score":0.2068996,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01350795768997696,"score_gpt":0.2667358145572244,"score_spread":0.2532278568672475,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}