{"id":"W1977759016","doi":"10.1038/srep00663","title":"Archaeal proteins Nop10 and Gar1 increase the catalytic activity of Cbf5 in pseudouridylating tRNA","year":2012,"lang":"en","type":"article","venue":"Scientific Reports","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Lethbridge","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Pseudouridine; Transfer RNA; Ribonucleoprotein; RNA; Uridine; Biochemistry; Chemistry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001090483,0.00006938227,0.00008148239,0.00004159705,0.0001150138,0.00002912008,0.00007164391,0.00004269139,0.000006542048],"category_scores_gemma":[0.0001309403,0.00005046589,0.00003303073,0.0001369275,0.0002425017,0.00001026098,0.00008591198,0.00006223105,8.000051e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001174772,"about_ca_system_score_gemma":0.00009716794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002838626,"about_ca_topic_score_gemma":0.0001321648,"domain_scores_codex":[0.9991744,0.0000426949,0.0001938109,0.0002609199,0.0001418139,0.0001863607],"domain_scores_gemma":[0.9991962,0.000008133348,0.0001674521,0.0005175676,0.00004780493,0.00006288919],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001389529,0.00008432329,0.04606105,0.00002053939,0.000008258279,0.000004120361,0.0002870698,0.00001686593,0.9470606,0.00003577452,0.0003824201,0.006025065],"study_design_scores_gemma":[0.0001989575,0.00004270662,0.126515,0.0000296482,0.00001721582,0.0001717118,0.0001556985,0.0001621067,0.8592391,0.0003828202,0.01291123,0.0001737735],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978203,0.0004710975,0.0001293342,0.00008379349,0.0003415555,0.0002384484,0.000003088766,0.000002972565,0.0009094495],"genre_scores_gemma":[0.9988493,0.000009920488,0.0001448135,0.000008732683,0.00007321222,0.00003717575,0.00001704877,0.0000062422,0.0008535843],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08782149,"threshold_uncertainty_score":0.2057939,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01376695348024993,"score_gpt":0.257936866023444,"score_spread":0.244169912543194,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}