{"id":"W1977759016","doi":"10.1038/srep00663","title":"Archaeal proteins Nop10 and Gar1 increase the catalytic activity of Cbf5 in pseudouridylating tRNA","year":2012,"lang":"en","type":"article","venue":"Scientific Reports","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Lethbridge","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Pseudouridine; Transfer RNA; Ribonucleoprotein; RNA; Uridine; Biochemistry; Chemistry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000131494,0.0003393595,0.0002103475,0.0001333608,0.0001154174,0.0002253482,0.0001583963,0.0002795345,0.001424029],"category_scores_gemma":[0.0001955469,0.0001237259,0.0002386093,0.00009047931,0.0002031895,0.0001676975,0.000244528,0.0003079961,0.000384359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003121105,"about_ca_system_score_gemma":0.0001639655,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007735854,"about_ca_topic_score_gemma":0.001379968,"domain_scores_codex":[0.999894,0.00001650542,0.00000461353,0.00002559925,0.00002803682,0.00003125002],"domain_scores_gemma":[0.9998791,0.00002940584,0.00002217834,0.00001123593,0.00001061217,0.00004745243],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009697172,0.00001199224,0.0003096199,0.00002927417,0.000003235052,0.00002971349,0.000008490783,0.00003280315,0.9984322,0.00004960484,0.00002578728,0.0009703483],"study_design_scores_gemma":[0.000009693132,0.0001087652,0.008396355,0.000005057086,0.000007832867,0.0001666323,0.00002470464,0.0005039863,0.9890372,0.00004239054,0.001693476,0.000003986089],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966238,0.00111673,0.0009832064,0.00009297272,0.00001628374,0.00000805016,0.000109675,0.00004584234,0.001003403],"genre_scores_gemma":[0.9950238,0.0004170425,0.001979238,0.00005037958,0.000004946967,0.000009127659,0.0003546263,0.00002179989,0.002139014],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001424029,"threshold_uncertainty_score":0.004763782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01376695348024993,"score_gpt":0.257936866023444,"score_spread":0.244169912543194,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}