{"id":"W1977840706","doi":"10.1016/s0828-282x(06)70983-7","title":"Matrix metalloproteinases in cardiovascular disease","year":2006,"lang":"en","type":"review","venue":"Canadian Journal of Cardiology","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":182,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; University Health Network; Toronto General Hospital; Heart and Stroke Foundation","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Matrix metalloproteinase; Medicine; Extracellular matrix; Myocardial infarction; MMP9; Dilated cardiomyopathy; Pathology; Vascular remodelling in the embryo; Proteolytic enzymes; Cardiology; Heart failure; Internal medicine; Cell biology; Biology; Enzyme; Biochemistry; Downregulation and upregulation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001425474,0.001429089,0.002180152,0.002928168,0.0005942664,0.001562313,0.001807515,0.001889191,0.003607024],"category_scores_gemma":[0.001524344,0.0004984273,0.0004540345,0.003618773,0.001222962,0.001626011,0.0008141134,0.00323279,0.002862768],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001437213,"about_ca_system_score_gemma":0.002954802,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005184723,"about_ca_topic_score_gemma":0.01284216,"domain_scores_codex":[0.9996519,0.00004373974,0.00004601133,0.00004990664,0.0001758316,0.00003264273],"domain_scores_gemma":[0.9991673,0.0002757742,0.0000717587,0.00002896671,0.0003510728,0.0001052589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001668278,0.000128459,0.000204579,0.006477265,0.00008644469,0.0004046986,0.00005665532,0.0003877096,0.001332853,0.003862169,0.1333031,0.8535892],"study_design_scores_gemma":[0.00005863147,0.00005229174,0.0006200974,0.001169467,0.00008622462,0.001170801,0.00004165397,0.0001072911,0.0002260748,0.00197309,0.9944773,0.00001707068],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005705196,0.9973305,0.0002052327,0.0005025914,0.0009274132,0.000004947774,0.00001217232,0.000008424871,0.0009515953],"genre_scores_gemma":[0.0005001353,0.9964059,0.0004226933,0.0002495048,0.001181624,0.000009002871,0.00002568524,0.000001786103,0.001203565],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005184723,"threshold_uncertainty_score":0.01206672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01982462560822024,"score_gpt":0.2634190537691802,"score_spread":0.2435944281609599,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}