{"id":"W1977890900","doi":"10.1038/mt.2012.146","title":"Phase II Trial of Intravenous Administration of Reolysin® (Reovirus Serotype-3-dearing Strain) in Patients with Metastatic Melanoma","year":2012,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":171,"is_retracted":false,"has_abstract":true,"ca_institutions":"Oncolytics Biotech (Canada)","funders":"National Cancer Institute","keywords":"Serotype; Virology; Strain (injury); Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008148891,0.001041307,0.001180039,0.0002256066,0.0003379151,0.0004320568,0.000356478,0.0007066184,0.002584905],"category_scores_gemma":[0.0004508265,0.0003923186,0.0005843145,0.0001410102,0.0005322088,0.0003051371,0.0001946598,0.00172327,0.0004573247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004177088,"about_ca_system_score_gemma":0.0006525164,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004233475,"about_ca_topic_score_gemma":0.0008784056,"domain_scores_codex":[0.9997982,0.00008510599,0.000009292105,0.00003691584,0.00001936292,0.00005111131],"domain_scores_gemma":[0.9996742,0.00005957991,0.00005433164,0.00003484794,0.00001914723,0.0001578445],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3583764,0.1263858,0.01204175,0.0008299171,0.0008538958,0.001193223,0.0006084567,0.004333795,0.3162419,0.0007243645,0.005702693,0.1727078],"study_design_scores_gemma":[0.1963025,0.7733354,0.01355601,0.00002987928,0.000164316,0.0006056462,0.00006037457,0.001606192,0.01028776,0.0001810677,0.003845782,0.00002512371],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946871,0.001030786,0.0006795626,0.0001752853,0.00008405599,0.001979296,0.0003127345,0.00005476476,0.0009964538],"genre_scores_gemma":[0.9915776,0.000776277,0.00167803,0.0004355603,0.0001272312,0.002021441,0.001000856,0.00001810024,0.002364901],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002584905,"threshold_uncertainty_score":0.008647382,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01446528722639093,"score_gpt":0.2636714118898322,"score_spread":0.2492061246634412,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}