{"id":"W1977899218","doi":"10.1016/j.yrtph.2014.06.024","title":"Acute and subchronic toxicity studies of pyrroloquinoline quinone (PQQ) disodium salt (BioPQQ™) in rats","year":2014,"lang":"en","type":"article","venue":"Regulatory Toxicology and Pharmacology","topic":"Microbial metabolism and enzyme function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":false,"ca_institutions":"Intertek (Canada)","funders":"","keywords":"Toxicity; Pyrroloquinoline quinone; Histopathology; Acute toxicity; Pharmacology; Chemistry; Physiology; Medicine; Endocrinology; Internal medicine; Toxicology; Biochemistry; Biology; Enzyme; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004494094,0.0002060525,0.00045414,0.0001092638,0.00008308421,0.000002929046,0.0001049146,0.0003477987,0.00004361701],"category_scores_gemma":[0.00004331872,0.000196236,0.0000466507,0.00009021024,0.0006477078,0.000009477253,0.0001896876,0.0001614191,0.000002260672],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001591442,"about_ca_system_score_gemma":0.00005085977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004914165,"about_ca_topic_score_gemma":0.0001148361,"domain_scores_codex":[0.9985301,0.000318262,0.0003407586,0.0004319894,0.00005060789,0.0003282976],"domain_scores_gemma":[0.9994794,0.00005802292,0.0001408122,0.0001733411,0.00005888714,0.00008953823],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006171898,0.000113826,0.002349015,0.00009495577,0.0001751325,0.000003873939,0.00009844887,0.00003454619,0.9910381,0.0004594451,0.003607288,0.001408186],"study_design_scores_gemma":[0.002368989,0.001010287,0.01641165,0.0000110073,0.0001511957,0.00006354402,0.00003660799,0.00009343013,0.9611903,0.000259556,0.01818467,0.0002187866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892688,0.009095765,0.00007460608,0.0004636126,0.0008023856,0.0002123777,0.00002420576,0.00001193479,0.00004628986],"genre_scores_gemma":[0.9940605,0.004157445,0.00009483369,0.001068155,0.0003464709,0.00002633651,0.00002623285,0.00001554295,0.0002044853],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02984781,"threshold_uncertainty_score":0.8002272,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01288676563916087,"score_gpt":0.2862191225367207,"score_spread":0.2733323568975598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}