{"id":"W1977981331","doi":"10.1158/0008-5472.can-05-3296","title":"BRCA1 DNA-Binding Activity Is Stimulated by BARD1","year":2006,"lang":"en","type":"article","venue":"Cancer Research","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Cancer Institute","keywords":"DNA repair; DNA; Ubiquitin; DNA damage; Biology; Cell biology; DNA-binding domain; DNA-binding protein; Transcription factor; Molecular biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004477523,0.0001206852,0.0001141133,0.00006480075,0.0001601273,0.00005027066,0.0002684874,0.0001789341,0.0002938641],"category_scores_gemma":[0.00004475744,0.0001217222,0.00006350807,0.0002221971,0.00009816125,0.000005076407,0.0001976194,0.0002247173,0.00007526386],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001077482,"about_ca_system_score_gemma":0.0001662456,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006314458,"about_ca_topic_score_gemma":0.00009390575,"domain_scores_codex":[0.9983813,0.0001240869,0.0001078828,0.0004655085,0.0003945561,0.0005266705],"domain_scores_gemma":[0.9992837,0.00001873579,0.00002923122,0.0004032627,0.0001654959,0.00009962417],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000068295,0.0000436572,0.0004873811,0.00001316443,0.00002352111,0.000004219687,0.000009415216,0.0000146046,0.9131244,0.00002411782,0.08440971,0.001777464],"study_design_scores_gemma":[0.0003730704,0.0001110302,0.0003315084,0.00001199525,0.00000376327,0.000001878859,0.00001141634,0.00008840636,0.9238674,0.0001090162,0.07495825,0.000132262],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995851,0.000576611,0.0001679783,0.0003594865,0.0001037862,0.0002326252,0.00009727761,0.00002558709,0.002585587],"genre_scores_gemma":[0.9846317,0.0001134204,0.00006591914,0.00007303736,0.0002458655,0.00007561516,0.00006925125,0.00003541779,0.01468977],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01210418,"threshold_uncertainty_score":0.4963688,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03576499160014329,"score_gpt":0.3725587902727699,"score_spread":0.3367937986726266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}