{"id":"W1977981331","doi":"10.1158/0008-5472.can-05-3296","title":"BRCA1 DNA-Binding Activity Is Stimulated by BARD1","year":2006,"lang":"en","type":"article","venue":"Cancer Research","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Cancer Institute","keywords":"DNA repair; DNA; Ubiquitin; DNA damage; Biology; Cell biology; DNA-binding domain; DNA-binding protein; Transcription factor; Molecular biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001411703,0.0002545697,0.0003024011,0.0003381641,0.0002086438,0.0004691435,0.0002689883,0.0002611228,0.003507195],"category_scores_gemma":[0.0002481071,0.0002329434,0.0003166454,0.0001667087,0.0002177702,0.0001638901,0.0004962996,0.0006840908,0.001140414],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004809171,"about_ca_system_score_gemma":0.00018167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005741105,"about_ca_topic_score_gemma":0.0007229593,"domain_scores_codex":[0.9996375,0.00004236535,0.00002214824,0.00009390392,0.0001017978,0.0001023015],"domain_scores_gemma":[0.9997101,0.00004081345,0.00007454173,0.00002723171,0.00002891674,0.0001183323],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001837215,0.00005180246,0.0002915085,0.00004094513,0.000004571191,0.00006719572,0.00001268169,0.00003691972,0.998096,0.00006727914,0.0001671343,0.0009803477],"study_design_scores_gemma":[0.00004497802,0.000231093,0.03542095,0.00001886866,0.00001269975,0.0004989105,0.00006824708,0.001930369,0.9550951,0.0001237626,0.006539781,0.00001514237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882857,0.004163052,0.00180326,0.000398287,0.0001166768,0.00002453879,0.0009506751,0.0002521152,0.004005781],"genre_scores_gemma":[0.9938096,0.0006143537,0.0007527919,0.0001642128,0.00002700422,0.00002859535,0.001463392,0.00003573312,0.003104287],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003507195,"threshold_uncertainty_score":0.01173276,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03576499160014329,"score_gpt":0.3725587902727699,"score_spread":0.3367937986726266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}