{"id":"W1978024916","doi":"10.1128/jb.01175-13","title":"Identification of Legionella pneumophila Effectors Regulated by the LetAS-RsmYZ-CsrA Regulatory Cascade, Many of Which Modulate Vesicular Trafficking","year":2013,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Legionella and Acanthamoeba research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Israel Science Foundation; Petroleum Technology Alliance Canada","keywords":"Effector; Biology; Legionella pneumophila; Secretion; Cell biology; Type three secretion system; Mutant; Golgi apparatus; Secretory pathway; Genetics; Gene; Endoplasmic reticulum; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008170985,0.0001742649,0.0004082344,0.0001218863,0.00007330124,0.00002075695,0.0004596914,0.0002817344,0.0000168055],"category_scores_gemma":[0.0001305578,0.0001207367,0.0002163539,0.0001929407,0.000302941,0.00002083533,0.00009126776,0.0002600621,0.000004712365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002382882,"about_ca_system_score_gemma":0.0001094823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004037181,"about_ca_topic_score_gemma":0.000003131496,"domain_scores_codex":[0.9980045,0.000365375,0.0008903854,0.0002265703,0.0002480549,0.0002650905],"domain_scores_gemma":[0.9978635,0.00005843012,0.0009608603,0.000437378,0.0005907691,0.00008903093],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001115686,0.00007005861,0.00119631,0.00004480118,0.0002183657,0.000003622791,0.00008707411,0.0004009851,0.9946231,0.00003169827,0.001912611,0.001299865],"study_design_scores_gemma":[0.000669637,0.0005040172,0.1201338,0.00004478084,0.00005908238,0.0002786414,0.00009044085,0.0003801654,0.876657,0.00007063241,0.0009701019,0.0001417398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975576,0.001103815,0.0001843042,0.0006120892,0.0002584954,0.0002336514,0.00000752649,0.000003288354,0.00003925777],"genre_scores_gemma":[0.9991462,0.0003618583,0.00002906016,0.00004613364,0.0002023607,0.000006027948,0.00002737836,0.00002435141,0.0001566527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1189375,"threshold_uncertainty_score":0.4923498,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007272309388726941,"score_gpt":0.2362595488659322,"score_spread":0.2289872394772052,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}