{"id":"W1978063542","doi":"10.2174/138161206776873671","title":"Glucagon and Glucagon-Like Peptide Receptors as Drug Targets","year":2006,"lang":"en","type":"review","venue":"Current Pharmaceutical Design","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital","funders":"","keywords":"Glucagon; Glucagon receptor; Glucose homeostasis; Glucagon-like peptide 1 receptor; Endocrinology; Internal medicine; Proglucagon; Gastric emptying; Liraglutide; Glucagon-like peptide-1; Glucagon-like peptide-2; Receptor; Enteroendocrine cell; Incretin; Biology; Chemistry; Type 2 diabetes; Insulin; Diabetes mellitus; Agonist; Medicine; Insulin resistance; Hormone; Biochemistry; Endocrine system; Peptide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005596213,0.001036425,0.002218065,0.0003862673,0.0001382843,0.0001129544,0.0002670804,0.0002428057,0.0005381464],"category_scores_gemma":[0.00007650096,0.0007942861,0.0006547825,0.000422117,0.000223428,0.0001352947,0.0002455339,0.0008749812,0.001308851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003618519,"about_ca_system_score_gemma":0.0002689839,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005456662,"about_ca_topic_score_gemma":2.979272e-7,"domain_scores_codex":[0.996103,0.0003926255,0.0008933416,0.001082239,0.0005995434,0.0009292743],"domain_scores_gemma":[0.9980126,0.0003825203,0.0002695797,0.0005110119,0.00007519501,0.0007490923],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004724481,0.0007247331,0.000009266385,0.01631803,0.0005455445,0.0001054038,0.00002008601,3.188297e-7,0.000001123319,0.0002695699,0.1389395,0.8430192],"study_design_scores_gemma":[0.001528805,0.0002369579,0.000003619351,0.008589458,0.008869289,0.00003719742,0.000005728989,0.00006133723,0.00005450771,0.00009859483,0.9798326,0.0006818764],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001324722,0.9884911,0.0004133923,0.0001354448,0.002639905,0.003850319,0.00002444702,0.0002496774,0.004182442],"genre_scores_gemma":[0.00001352649,0.9875563,0.000727691,0.0002089102,0.0006574226,0.0004843864,0.0007290866,0.0001464308,0.009476287],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8423373,"threshold_uncertainty_score":0.9994687,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1196827037513834,"score_gpt":0.4127838289377669,"score_spread":0.2931011251863835,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}