{"id":"W1978072628","doi":"10.1128/jvi.74.6.2913-2919.2000","title":"Herpes Simplex Virus ICP27 Induces Cytoplasmic Accumulation of Unspliced Polyadenylated α-Globin Pre-mRNA in Infected HeLa Cells","year":2000,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; McMaster University","funders":"","keywords":"Biology; RNA splicing; Polyadenylation; Molecular biology; RNA; Intron; Globin; Cell biology; Messenger RNA; Cytoplasm; Herpes simplex virus; HeLa; Virology; Gene; Cell culture; Virus; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002183407,0.0003599625,0.0003377713,0.0003644653,0.0002253493,0.0004130111,0.0002364532,0.0001752247,0.001699793],"category_scores_gemma":[0.0002526553,0.0002255322,0.0002846454,0.0002453297,0.0003480953,0.0001680719,0.0003436014,0.0006546629,0.0007478633],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006635016,"about_ca_system_score_gemma":0.0004103263,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009409895,"about_ca_topic_score_gemma":0.0009429703,"domain_scores_codex":[0.9997899,0.00003297057,0.00002143734,0.00003612238,0.00007064571,0.00004895338],"domain_scores_gemma":[0.9997687,0.00006866735,0.00003191438,0.00004985086,0.00003460522,0.00004635259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004289873,0.00001449463,0.00009706557,0.00001852902,0.000003527483,0.00005207253,0.0000248284,0.00003270421,0.9989668,0.0001350244,0.00005332676,0.0005587107],"study_design_scores_gemma":[0.00001068372,0.0001110035,0.00128094,0.000003758309,0.00000725785,0.0001132992,0.00002283077,0.0004149713,0.9963347,0.00005382429,0.001644148,0.000002646688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855769,0.001198954,0.006363684,0.0001033634,0.00006989192,0.0000871139,0.0009083858,0.0002718779,0.005419801],"genre_scores_gemma":[0.9846371,0.001010714,0.005966976,0.00006214181,0.00003473524,0.00009354112,0.001888349,0.0001309817,0.006175537],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001699793,"threshold_uncertainty_score":0.005686402,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03047236874590627,"score_gpt":0.3414519278376963,"score_spread":0.31097955909179,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}