{"id":"W1978085487","doi":"10.1016/j.reprotox.2013.10.009","title":"Sub-chronic sulforaphane exposure in CD-1 pregnant mice enhances maternal NADPH quinone oxidoreductase 1 (NQO1) activity and mRNA expression of NQO1, glutathione S-transferase, and glutamate-cysteine ligase: Potential implications for fetal protection against toxicant exposure","year":2013,"lang":"en","type":"article","venue":"Reproductive Toxicology","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research","keywords":"GCLC; Sulforaphane; GCLM; Glutathione; Fetus; Endocrinology; Internal medicine; Chemistry; Medicine; Pharmacology; Biology; Pregnancy; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001661311,0.0005879847,0.0004284726,0.0008174742,0.0002873786,0.0004055129,0.0003550519,0.0006369213,0.001974154],"category_scores_gemma":[0.000165794,0.0004469357,0.0002775344,0.0002448943,0.000879266,0.0003699799,0.0002673969,0.00124693,0.0002983146],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005238039,"about_ca_system_score_gemma":0.0004060043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001362536,"about_ca_topic_score_gemma":0.003417122,"domain_scores_codex":[0.9997465,0.00002902286,0.00001758812,0.0001005955,0.00004704415,0.00005914264],"domain_scores_gemma":[0.9996081,0.00003857288,0.0001507493,0.00004819133,0.00002161189,0.0001329015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008580706,0.00007254773,0.0005812509,0.00001612974,0.000006755929,0.00006069091,0.00002918621,0.00003094162,0.9973298,0.00009132786,0.00002568614,0.000897687],"study_design_scores_gemma":[0.0000845671,0.001199568,0.01039615,0.00001163069,0.00006671523,0.0002876116,0.0001470504,0.0003757979,0.9861755,0.000174488,0.001072021,0.000009087945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969162,0.0005617241,0.001219926,0.0001869788,0.00002831975,0.0000150937,0.0004606399,0.0001015642,0.0005095861],"genre_scores_gemma":[0.9909551,0.0007769997,0.001878374,0.0001218258,0.00001807007,0.00005587016,0.0004223475,0.00005023026,0.005721178],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001974154,"threshold_uncertainty_score":0.006604254,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008330691840542534,"score_gpt":0.2344456739466703,"score_spread":0.2261149821061278,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}