{"id":"W1978086164","doi":"10.1182/blood-2008-11-187419","title":"Enrichment of Sca1+ hematopoietic progenitors in polycythemic mice inhibits leukemogenesis","year":2009,"lang":"en","type":"article","venue":"Blood","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Health Sciences Centre; Sunnybrook Health Science Centre","funders":"","keywords":"Haematopoiesis; Progenitor cell; Polycythemia vera; Biology; Erythropoietin receptor; Cancer research; Erythropoietin; CD34; Leukemia; Immunology; Stem cell; Molecular biology; Cell biology; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001860298,0.0006157925,0.000441361,0.0006296266,0.0002022796,0.0003437975,0.0003109669,0.0004616078,0.001440209],"category_scores_gemma":[0.0001160937,0.0001855324,0.0001640593,0.0002044896,0.0002933798,0.0002112137,0.0002063455,0.0009615371,0.0004680871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001916185,"about_ca_system_score_gemma":0.0001757534,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003190876,"about_ca_topic_score_gemma":0.0007394144,"domain_scores_codex":[0.9997346,0.00004809461,0.00002677244,0.00005955982,0.00006718149,0.00006375617],"domain_scores_gemma":[0.9997711,0.00002929898,0.00007056506,0.00002953857,0.00001309019,0.0000864742],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000339145,0.0002474628,0.0002326088,0.00003974177,0.000009617913,0.00007576395,0.00002080824,0.000158558,0.9949237,0.0002289497,0.000109413,0.00361435],"study_design_scores_gemma":[0.0002645959,0.004656882,0.005479944,0.00002365833,0.00007839947,0.0009113446,0.00002627789,0.002152945,0.9792667,0.0001103531,0.007016159,0.00001273349],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920688,0.002320558,0.00240615,0.0001250891,0.00004757338,0.0001004307,0.0003656,0.000285572,0.00228019],"genre_scores_gemma":[0.9914405,0.001454092,0.002628596,0.00008648164,0.0000361828,0.0001334635,0.0005893816,0.00005266343,0.003578676],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001440209,"threshold_uncertainty_score":0.004817963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0101848069667596,"score_gpt":0.2534026142587871,"score_spread":0.2432178072920275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}