{"id":"W1978101826","doi":"10.3324/haematol.2010.027086","title":" -catenin is constitutively active and increases STAT3 expression/activation in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma","year":2010,"lang":"en","type":"article","venue":"Haematologica","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Terry Fox Foundation; Alberta Cancer Foundation; Cancer Research Institute","keywords":"Anaplastic large-cell lymphoma; Anaplastic lymphoma kinase; Cancer research; Lymphoma; Biology; Cell growth; Cell culture; Catenin; Signal transduction; Pathology; Wnt signaling pathway; Medicine; Cell biology; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000121827,0.0002895594,0.0003028946,0.0001137661,0.0001908777,0.00004308501,0.0001779861,0.0003070243,0.000103594],"category_scores_gemma":[0.0002320764,0.0002502738,0.00005334269,0.0001665044,0.0002630558,0.00002208059,0.0001722098,0.0001103882,0.00001937954],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003367822,"about_ca_system_score_gemma":0.0002172176,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006529043,"about_ca_topic_score_gemma":0.0001105643,"domain_scores_codex":[0.9984676,0.00008862017,0.0002809511,0.0005915807,0.0001680089,0.0004033017],"domain_scores_gemma":[0.9992571,0.000138302,0.0001724833,0.000187879,0.0001165929,0.0001275714],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002001488,0.000949624,0.01713072,0.00007408531,0.00007537968,0.0001171035,0.0005240724,0.000006678943,0.9713203,0.00065678,0.003812614,0.00333113],"study_design_scores_gemma":[0.003045072,0.0002879138,0.03715231,0.0000918188,0.00002159589,0.00007309295,0.0003793306,0.00006001132,0.9552038,0.0002428981,0.003039957,0.000402255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967644,0.0001551915,0.0009547322,0.00005885663,0.0001357036,0.0002672957,0.0001234976,0.00002875014,0.001511602],"genre_scores_gemma":[0.9980726,0.00008159081,0.001004647,0.0003158084,0.00005295433,0.0000918893,0.0001918477,0.00002039387,0.0001682362],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02002159,"threshold_uncertainty_score":0.9999949,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007329888307830495,"score_gpt":0.226795285981008,"score_spread":0.2194653976731775,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}