{"id":"W1978101826","doi":"10.3324/haematol.2010.027086","title":" -catenin is constitutively active and increases STAT3 expression/activation in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma","year":2010,"lang":"en","type":"article","venue":"Haematologica","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Terry Fox Foundation; Alberta Cancer Foundation; Cancer Research Institute","keywords":"Anaplastic large-cell lymphoma; Anaplastic lymphoma kinase; Cancer research; Lymphoma; Biology; Cell growth; Cell culture; Catenin; Signal transduction; Pathology; Wnt signaling pathway; Medicine; Cell biology; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001778842,0.0002493343,0.0001893054,0.0005182948,0.0002088052,0.0004424826,0.0001471555,0.0003096785,0.002429709],"category_scores_gemma":[0.0001879583,0.0001401448,0.0002523585,0.0003046232,0.0002655334,0.000179975,0.0001485545,0.000531265,0.0005334195],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004021293,"about_ca_system_score_gemma":0.0001734737,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000364364,"about_ca_topic_score_gemma":0.0007800058,"domain_scores_codex":[0.9998286,0.00002175041,0.00001391522,0.00002772684,0.00007046005,0.00003752326],"domain_scores_gemma":[0.999866,0.00002471487,0.00004317999,0.00001276136,0.00001411912,0.00003928176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001673687,0.00005617068,0.001727423,0.00003833771,0.000007535491,0.0002023228,0.00001874544,0.00003168563,0.9966596,0.0000551237,0.00007392946,0.0009617817],"study_design_scores_gemma":[0.0001712033,0.001486443,0.1028195,0.00002560201,0.0001107508,0.004779479,0.000232368,0.002028421,0.8801998,0.0002275452,0.007903411,0.00001547076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963484,0.001842791,0.0004733954,0.00007237412,0.00002174475,0.00001549041,0.0002132021,0.00005082355,0.000961745],"genre_scores_gemma":[0.9984366,0.000335149,0.0002345484,0.0000288929,0.00000769433,0.00001464031,0.000326678,0.000003888004,0.0006118907],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002429709,"threshold_uncertainty_score":0.008128226,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007329888307830495,"score_gpt":0.226795285981008,"score_spread":0.2194653976731775,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}