{"id":"W1978252394","doi":"10.1016/j.neurobiolaging.2011.07.014","title":"Detrimental effects of arachidonic acid and its metabolites in cellular and mouse models of Alzheimer's disease: structural insight","year":2011,"lang":"en","type":"article","venue":"Neurobiology of Aging","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":98,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research; University Research Committee, Emory University","keywords":"Arachidonic acid; Disease; Neuroscience; Chemistry; Biology; Cell biology; Biochemistry; Medicine; Internal medicine; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002244879,0.0005729435,0.0002778039,0.0008450925,0.0002738227,0.0004567056,0.0003700097,0.0005469199,0.0006893592],"category_scores_gemma":[0.0001473109,0.0002401073,0.0003250972,0.0002697583,0.0004475957,0.0006376657,0.0003017129,0.0007433663,0.0001514073],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003271686,"about_ca_system_score_gemma":0.000405682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001128273,"about_ca_topic_score_gemma":0.001922116,"domain_scores_codex":[0.9999135,0.00001545623,0.000008880305,0.00001334305,0.00002400423,0.00002499185],"domain_scores_gemma":[0.9998702,0.00001913521,0.00004785169,0.00001947845,0.00002243989,0.000020995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004569906,0.00004217103,0.0003812123,0.00009661914,0.00002064532,0.0002533899,0.00002674074,0.0001191236,0.9941173,0.001676245,0.00006017286,0.002749496],"study_design_scores_gemma":[0.00005048263,0.0004867781,0.01086468,0.00002736778,0.0001471497,0.001097756,0.0001543224,0.0006935297,0.9790581,0.00246727,0.004938728,0.00001384078],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9604594,0.02166479,0.01101656,0.001357716,0.0001199349,0.00003752549,0.0007413605,0.0001208723,0.004481847],"genre_scores_gemma":[0.9823584,0.01252728,0.002956825,0.0001607458,0.00003130274,0.00002052281,0.0002789496,0.00001253797,0.00165341],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001128273,"threshold_uncertainty_score":0.002373815,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02727801461591322,"score_gpt":0.2699001330860035,"score_spread":0.2426221184700903,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}