{"id":"W1978278499","doi":"10.1016/j.bbrc.2012.04.078","title":"Structural insights into the metabolism of 2-chlorodibenzofuran by an evolved biphenyl dioxygenase","year":2012,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Metal-Catalyzed Oxygenation Mechanisms","field":"Chemistry","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada; Indian Institute of Technology Roorkee","keywords":"Dibenzofuran; Dioxygenase; Chemistry; Biphenyl; Stereochemistry; Substrate (aquarium); Oxygenase; Active site; Enzyme; Biochemistry; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001106146,0.0002820131,0.0001862963,0.0001106562,0.0002236596,0.0003761259,0.0002847027,0.0003460802,0.0005832084],"category_scores_gemma":[0.0001232325,0.0001161537,0.0001714324,0.0001320235,0.0002046193,0.0002526558,0.0001443492,0.0006260396,0.0002137306],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006626179,"about_ca_system_score_gemma":0.0003501125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002424981,"about_ca_topic_score_gemma":0.00259962,"domain_scores_codex":[0.9999605,0.000004203519,0.000001930115,0.00000601011,0.00001620274,0.00001118236],"domain_scores_gemma":[0.9999578,0.000007803657,0.00001168515,0.000003574254,0.000006565651,0.00001261136],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002551095,0.00008521407,0.001144401,0.00006252799,0.0000100529,0.0004465618,0.00007920737,0.002846093,0.9888826,0.002082357,0.0001634233,0.003942531],"study_design_scores_gemma":[0.00008388734,0.0003836694,0.01450063,0.00001672001,0.00005773807,0.001085419,0.0003270574,0.02984412,0.9415856,0.001933326,0.01014019,0.00004170481],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944982,0.0005373975,0.003203647,0.0004256933,0.00001675851,0.000006025677,0.0001619963,0.0000739917,0.0010764],"genre_scores_gemma":[0.996178,0.0006716106,0.002050094,0.00004599535,0.000008795058,0.000002652831,0.000369898,0.00001029438,0.0006626337],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002424981,"threshold_uncertainty_score":0.004821658,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06948441457416066,"score_gpt":0.35018057221113,"score_spread":0.2806961576369693,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}