{"id":"W1978316906","doi":"10.2353/ajpath.2009.090042","title":"Targeted Overexpression of EZH2 in the Mammary Gland Disrupts Ductal Morphogenesis and Causes Epithelial Hyperplasia","year":2009,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Tumors and Oncological Cases","field":"Medicine","cited_by":115,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; Fashion Footwear Association of New York; McGill University; Avon Foundation for Women","keywords":"Morphogenesis; Mammary gland; Pathology; Biology; Hyperplasia; Epithelium; Cancer research; Cancer; Medicine; Breast cancer; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000114481,0.0003495527,0.0003138375,0.0004946058,0.0002280109,0.0003721777,0.0002412553,0.0004818641,0.001809662],"category_scores_gemma":[0.000178512,0.0002478548,0.0002411148,0.0002775707,0.0004295898,0.0002053185,0.0003603277,0.0005339544,0.0004356889],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003680917,"about_ca_system_score_gemma":0.0002010419,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005403282,"about_ca_topic_score_gemma":0.001086585,"domain_scores_codex":[0.9998293,0.0000196669,0.00001528963,0.00002987087,0.00006338062,0.00004253466],"domain_scores_gemma":[0.9998785,0.00003425191,0.00003008083,0.00001956404,0.000005180821,0.00003243066],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002186875,0.00004655037,0.001044469,0.00002851332,0.00001940586,0.00168365,0.0000231615,0.0002274606,0.9939588,0.0005225383,0.0001386232,0.002088016],"study_design_scores_gemma":[0.00004885064,0.0002518387,0.01125928,0.000002722906,0.00005552157,0.006870976,0.00009486495,0.001477611,0.9763262,0.0002553705,0.00334739,0.000009361852],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954023,0.0006523383,0.001685458,0.0001834614,0.00004077287,0.00001598317,0.0002322201,0.0001358355,0.001651514],"genre_scores_gemma":[0.9978133,0.0002145511,0.0003619605,0.00002929235,0.000006681795,0.000005259201,0.0001094082,0.00001565743,0.001443757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001809662,"threshold_uncertainty_score":0.006053925,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01110934284825794,"score_gpt":0.2803774469598472,"score_spread":0.2692681041115893,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}