{"id":"W1978476146","doi":"10.1074/jbc.m703654200","title":"RPE65 from Cone-dominant Chicken Is a More Efficient Isomerohydrolase Compared with That from Rod-dominant Species","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Research Resources; National Eye Institute","keywords":"RPE65; Visual phototransduction; Retinal; Retinal pigment epithelium; Cis-trans-Isomerases; Scotopic vision; Biology; Retina; Cell biology; Recombinant DNA; Biochemistry; Chemistry; Enzyme","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001289489,0.0003218561,0.0005248156,0.00002545795,0.0001282065,0.0000259951,0.0004129779,0.0002725059,0.0002755602],"category_scores_gemma":[0.00009606827,0.0001990567,0.000245462,0.0000887907,0.0004389028,0.000006022817,0.0001370799,0.0002667914,0.000009937477],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003153763,"about_ca_system_score_gemma":0.0001355361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002700347,"about_ca_topic_score_gemma":0.000002028429,"domain_scores_codex":[0.9983988,0.00004140078,0.0004873071,0.0004065459,0.0003370116,0.0003289818],"domain_scores_gemma":[0.9988368,0.00005389689,0.0004687221,0.000278498,0.0001410872,0.0002209541],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001872509,0.0002476008,0.05997482,0.000008494922,0.0001815176,0.0002153303,0.0002082351,0.00003715118,0.9342433,3.695266e-7,0.002949827,0.00006089529],"study_design_scores_gemma":[0.002344393,0.0002649206,0.0583496,0.0000663177,0.00004176684,0.0002011875,0.0005942004,0.00004884683,0.9267637,0.00002441975,0.01095637,0.0003442797],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961962,0.002016686,0.0003862297,0.0004256594,0.00009318384,0.00009660186,0.00009944907,0.000006069237,0.0006799157],"genre_scores_gemma":[0.9969032,0.0009637247,0.0009017413,0.0003176543,0.0003253495,0.000004886039,0.0002091819,0.0000158329,0.0003583748],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008006543,"threshold_uncertainty_score":0.8117295,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02134349173990271,"score_gpt":0.2276562117148084,"score_spread":0.2063127199749057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}