{"id":"W1978517331","doi":"10.1016/j.bbapap.2005.07.039","title":"Tetrabromobenzotriazole (TBBt) and tetrabromobenzimidazole (TBBz) as selective inhibitors of protein kinase CK2: Evaluation of their effects on cells and different molecular forms of human CK2","year":2005,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Protein subunit; In vitro; Kinase; Gene isoform; Protein kinase A; Biochemistry; Isozyme; Gene knockdown; Biology; Cell biology; Chemistry; Enzyme; Apoptosis; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002905586,0.0008953447,0.001058281,0.0008841294,0.0001694563,0.0004187638,0.0008422738,0.0005560757,0.001135786],"category_scores_gemma":[0.0001943415,0.0002760479,0.0003216873,0.0009339463,0.0003016666,0.0004667488,0.0001991687,0.001028387,0.001167557],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006065195,"about_ca_system_score_gemma":0.0003522983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001599815,"about_ca_topic_score_gemma":0.0034625,"domain_scores_codex":[0.9999101,0.000009806564,0.000009181051,0.00001704653,0.00003457647,0.0000192739],"domain_scores_gemma":[0.9999316,0.00002292784,0.00001323683,0.000004178951,0.00001874788,0.00000935099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006550173,0.0003057209,0.0002656929,0.004708137,0.0001137701,0.0005330255,0.00008585086,0.0009326772,0.1992618,0.002747721,0.009548318,0.7808422],"study_design_scores_gemma":[0.0002827887,0.001456593,0.00356544,0.0004560341,0.0003882825,0.003503344,0.00007330634,0.0007195208,0.2411395,0.0008943499,0.7474478,0.00007309049],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009615642,0.982515,0.0029181,0.0002776992,0.0002664471,0.00004379452,0.00009487579,0.0001171394,0.004151318],"genre_scores_gemma":[0.032721,0.9574575,0.002424164,0.0002865107,0.0000971395,0.00005124948,0.0002362736,0.00001769585,0.006708432],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001599815,"threshold_uncertainty_score":0.004400671,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01783272422829648,"score_gpt":0.2927982324967857,"score_spread":0.2749655082684893,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}