{"id":"W1978560245","doi":"10.1161/circresaha.112.264903","title":"Translational Success Stories","year":2012,"lang":"en","type":"review","venue":"Circulation Research","topic":"Heparin-Induced Thrombocytopenia and Thrombosis","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"Thrombosis and Atherosclerosis Research Institute; McMaster University; Population Health Research Institute","funders":"","keywords":"Argatroban; Discovery and development of direct thrombin inhibitors; Bivalirudin; Lepirudin; Medicine; Dabigatran; Direct thrombin inhibitor; Hirudin; Antithrombotic; Ximelagatran; Thrombin; Pharmacology; Anticoagulant; Antithrombins; Heparin; Percutaneous coronary intervention; Intensive care medicine; Warfarin; Antithrombin; Surgery; Internal medicine; Platelet; Atrial fibrillation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.001652499,0.0003210082,0.001479165,0.0007633092,0.0003311053,0.0000992382,0.0002474758,0.0006122935,0.002030824],"category_scores_gemma":[0.0001739684,0.0002715969,0.0004530783,0.001271533,0.0002106096,0.0002560157,0.00007487201,0.001309233,0.001529411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000381654,"about_ca_system_score_gemma":0.001339879,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001033084,"about_ca_topic_score_gemma":0.00002028917,"domain_scores_codex":[0.9963478,0.0005617951,0.0006346781,0.0005088552,0.001255439,0.000691391],"domain_scores_gemma":[0.9977812,0.000530732,0.0001221097,0.0006427563,0.0005280531,0.0003951564],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000009612377,0.0001834461,0.002967943,0.0156414,0.0003718484,0.00001353199,0.000250221,0.00000117239,0.00001051996,0.004293325,0.0002672668,0.9759897],"study_design_scores_gemma":[0.0002812608,0.00003079256,0.01214094,0.003101685,0.0006739263,0.00007868905,0.00001700204,0.00001438667,0.000002069283,0.0001401632,0.9832645,0.0002545791],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003624374,0.981209,0.00005475833,0.0001817775,0.0003351976,0.001608938,0.00003055733,0.00007805802,0.01613923],"genre_scores_gemma":[0.04023609,0.9565224,0.00008446228,0.00001237846,0.001111508,0.0002307509,0.0007761266,0.00009649625,0.0009297745],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9829972,"threshold_uncertainty_score":0.9999736,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.5385920438495161,"score_gpt":0.5421676590813999,"score_spread":0.003575615231883766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}