{"id":"W1978572699","doi":"10.1016/j.virusres.2014.02.013","title":"The conserved sumoylation consensus site in TRIM5α modulates its immune activation functions","year":2014,"lang":"en","type":"article","venue":"Virus Research","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"Canadian Institutes of Health Research","keywords":"SUMO protein; Biology; Ubiquitin ligase; Ubiquitin; Innate immune system; Cell biology; Zinc finger; Transcription factor; Genetics; Immune system; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002236806,0.0001123807,0.000156687,0.000298588,0.0009142817,0.0000627502,0.0001846262,0.0001612831,0.000284158],"category_scores_gemma":[0.001436828,0.00007810075,0.00005379364,0.0005222027,0.0003546837,0.00006479825,0.0001019798,0.0006394891,0.006426509],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000142222,"about_ca_system_score_gemma":0.0001496674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002303166,"about_ca_topic_score_gemma":0.001645671,"domain_scores_codex":[0.9970092,0.001653119,0.0002727083,0.0002723032,0.0001417403,0.0006508872],"domain_scores_gemma":[0.9966859,0.002566502,0.00004495987,0.000365707,0.0002984772,0.00003845681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007959875,0.0001918245,0.004590206,0.000009628633,0.00008788476,0.00000383047,0.0002281913,0.00004415383,0.9609032,0.0008474974,0.004452286,0.02784534],"study_design_scores_gemma":[0.005290181,0.0007582583,0.2693067,0.00005751249,0.00001041416,0.00001517288,0.0004657991,0.0007893494,0.5096943,0.0008231324,0.2125588,0.0002303641],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917982,0.001686387,0.00003278182,0.002488014,0.0001252279,0.0006093091,0.00004387892,0.00004025186,0.003175915],"genre_scores_gemma":[0.9882095,0.0002404361,0.000006762736,0.00001424888,0.00002498495,0.0001478146,0.0002468425,0.00001302971,0.01109636],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4512089,"threshold_uncertainty_score":0.9943471,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06918553204928517,"score_gpt":0.3444309790895715,"score_spread":0.2752454470402863,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}