{"id":"W1978614909","doi":"10.1042/bj20112158","title":"Identification of novel signalling roles and targets for Gα and Gβγ downstream of the insulin-like growth factor 1 receptor in vascular smooth muscle cells","year":2012,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"","keywords":"Signalling; Downstream (manufacturing); Cell biology; Vascular smooth muscle; Receptor; Growth factor; Insulin-like growth factor; Signalling pathways; Biology; Growth factor receptor; Internal medicine; Endocrinology; Smooth muscle; Signal transduction; Biochemistry; Medicine; Business","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006030594,0.0002759037,0.0002001119,0.0002978971,0.0001556752,0.0002127694,0.0001723841,0.0003031511,0.000903557],"category_scores_gemma":[0.00006239322,0.0001127315,0.0002357213,0.0001757278,0.0001353914,0.0001292942,0.0001462129,0.000281533,0.0003575212],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000269239,"about_ca_system_score_gemma":0.0001556834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003805952,"about_ca_topic_score_gemma":0.000587802,"domain_scores_codex":[0.9999605,0.000005117212,0.000002141034,0.000009649942,0.00001160399,0.00001100346],"domain_scores_gemma":[0.9999689,0.000003191387,0.000008340399,0.000002310997,0.000004078314,0.00001321299],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001270766,0.00001610351,0.0003018151,0.00004658131,0.000004900091,0.0001891532,0.00001296636,0.00003804079,0.9975947,0.0001456437,0.000042953,0.001480108],"study_design_scores_gemma":[0.0001539083,0.0009594447,0.1362029,0.00005617006,0.0001395722,0.003454049,0.0002549533,0.003141476,0.8391183,0.0007114993,0.01578676,0.00002093824],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885314,0.005612109,0.002588035,0.000432727,0.00003478745,0.0000440814,0.0002570356,0.00005923699,0.002440586],"genre_scores_gemma":[0.9884693,0.00445545,0.002746199,0.0002178309,0.00003198506,0.00004786283,0.0007872459,0.000008173275,0.003236107],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000903557,"threshold_uncertainty_score":0.003022671,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0147393500519787,"score_gpt":0.235777817387929,"score_spread":0.2210384673359503,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}